专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08409814B2 Sensor proteins and assay methods 有权
标题翻译：传感器蛋白和测定方法
公开(公告)号：US08409814B2
公开(公告)日：2013-04-02
申请号：US12874140
申请日：2010-09-01
申请人： Kurt Vogel , Rhonda Newman , Steven Riddle
发明人： Kurt Vogel , Rhonda Newman , Steven Riddle
IPC分类号： G01N33/53 , G01N33/00 , C07K1/00 , C07K14/00 , C07K16/00 , C07K17/00
CPC分类号： G01N33/542 , G01N33/84 , Y10T436/16
摘要： The present invention relates to biosensors. In some embodiments, the biosensors are modified ligand binding molecules. In some embodiments, the modified ligand binding molecule is a phosphate binding protein (PBP). In some embodiments, the modified ligand binding molecules are labeled to be capable of RET, e.g., comprising a donor and acceptor moiety. In some embodiments of the invention, there is a detectable change in RET (e.g., FRET) when the modified ligand binding molecule binds and/or releases the ligand (e.g., phosphate). The invention also provides related methods, reactions and assays.
摘要翻译：本发明涉及生物传感器。在一些实施方案中，生物传感器是修饰的配体结合分子。在一些实施方案中，修饰的配体结合分子是磷酸结合蛋白（PBP）。在一些实施方案中，修饰的配体结合分子被标记为能够RET，例如包含供体和受体部分。在本发明的一些实施方案中，当修饰的配体结合分子结合和/或释放配体（例如磷酸盐）时，在RET（例如，FRET）中存在可检测的变化。本发明还提供相关方法，反应和测定。

2. 发明申请

US20070142759A1 Orthopedic night foot splint 有权
标题翻译：骨科夜间夹板
公开(公告)号：US20070142759A1
公开(公告)日：2007-06-21
申请号：US11701772
申请日：2007-02-02
申请人： E. Slautterback , Rhonda Newman , Daniel Bozza
发明人： E. Slautterback , Rhonda Newman , Daniel Bozza
IPC分类号： A61F5/00
CPC分类号： A61F5/0111
摘要： A foot splint for the prevention and rehabilitation of plantar fasciitis by maintaining a wearer's foot and, hence, his plantar fascia in a pre-selected amount of dorsiflexion. The foot splint includes a footplate for supporting the wearer's foot, a bracket integrally attached to the footplate near the heel region, where the bracket has at least one ankle angle preset, a strut (either medial, lateral, or both sides) extending along the lower leg of the wearer, a strut sleeve removably enveloping the strut. The sleeve has an upper end and a lower end, and the strut protrudes from the lower end of the sleeves. There is an adjustable leg strap attached to the strut sleeve at the upper end. The strap secures the upper end to the leg of a wearer during operation. A padded insole may be provided to cushion the wearer's foot from the footplate. The foot splint provides a comfortable “slipper-like” feel for the wearer.
摘要翻译：足底夹板，用于通过保持佩戴者的脚，并因此将其足底筋膜预先选定的背屈量来预防和修复足底筋膜炎。脚夹板包括用于支撑佩戴者的脚的脚板，在鞋跟区域附近一体地附接到脚板的支架，其中支架具有至少一个脚踝角度预设，沿着该支架延伸的支柱（内侧，外侧或两侧）穿着者的小腿，可移除地包围支柱的支柱套管。套筒具有上端和下端，支柱从套筒的下端突出。在上端有一个可调节的腿带，附着在支柱套上。在操作过程中，表带将上端固定在佩戴者的腿部上。可以提供衬垫的鞋内底以从脚板缓冲佩戴者的脚。脚夹板为穿戴者提供了舒适的“拖鞋式”感觉。

3. 发明申请

US20110111422A1 SENSOR PROTEINS AND ASSAY METHODS 有权
标题翻译：传感器蛋白质和测定方法
公开(公告)号：US20110111422A1
公开(公告)日：2011-05-12
申请号：US12874140
申请日：2010-09-01
申请人： Kurt VOGEL , Rhonda Newman , Steven Riddle
发明人： Kurt VOGEL , Rhonda Newman , Steven Riddle
IPC分类号： G01N33/53 , C07K14/00 , C07K14/245
CPC分类号： G01N33/542 , G01N33/84 , Y10T436/16
摘要： The present invention relates to biosensors. In some embodiments, the biosensors are modified ligand binding molecules. In some embodiments, the modified ligand binding molecule is a phosphate binding protein (PBP). In some embodiments, the modified ligand binding molecules are labeled to be capable of RET, e.g., comprising a donor and acceptor moiety. In some embodiments of the invention, there is a detectable change in RET (e.g., FRET) when the modified ligand binding molecule binds and/or releases the ligand (e.g., phosphate). The invention also provides related methods, reactions and assays.
摘要翻译：本发明涉及生物传感器。在一些实施方案中，生物传感器是修饰的配体结合分子。在一些实施方案中，修饰的配体结合分子是磷酸结合蛋白（PBP）。在一些实施方案中，修饰的配体结合分子被标记为能够RET，例如包含供体和受体部分。在本发明的一些实施方案中，当修饰的配体结合分子结合和/或释放配体（例如磷酸盐）时，在RET（例如，FRET）中存在可检测的变化。本发明还提供相关方法，反应和测定。

4. 发明申请

US20080213811A1 SENSOR PROTEINS AND ASSAY METHODS 审中-公开
标题翻译：传感器蛋白质和测定方法
公开(公告)号：US20080213811A1
公开(公告)日：2008-09-04
申请号：US11837180
申请日：2007-08-10
申请人： Kurt Vogel , Rhonda Newman , Steven Riddle
发明人： Kurt Vogel , Rhonda Newman , Steven Riddle
IPC分类号： C12Q1/44 , G01N33/48 , C12Q1/48
CPC分类号： G01N33/542 , G01N33/84 , Y10T436/16
摘要： The present invention relates to biosensors. In some embodiments, the biosensors are modified ligand binding molecules. In some embodiments, the modified ligand binding molecule is a phosphate binding protein (PBP). In some embodiments, the modified ligand binding molecules are labeled to be capable of RET, e.g., comprising a donor and acceptor moiety. In some embodiments of the invention, there is a detectable change in RET (e.g., FRET) when the modified ligand binding molecule binds and/or releases the ligand (e.g., phosphate). The invention also provides related methods, reactions and assays.
摘要翻译：本发明涉及生物传感器。在一些实施方案中，生物传感器是修饰的配体结合分子。在一些实施方案中，修饰的配体结合分子是磷酸结合蛋白（PBP）。在一些实施方案中，修饰的配体结合分子被标记为能够RET，例如包含供体和受体部分。在本发明的一些实施方案中，当修饰的配体结合分子结合和/或释放配体（例如磷酸盐）时，在RET（例如，FRET）中存在可检测的变化。本发明还提供相关方法，反应和测定。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式