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1. 发明授权

US08221359B2 Injection device with cap 有权
标题翻译：注射装置带盖
公开(公告)号：US08221359B2
公开(公告)日：2012-07-17
申请号：US11663185
申请日：2005-09-08
申请人： Johnny Kristensen , Jim Radmer , Peter Christian Klitgaard
发明人： Johnny Kristensen , Jim Radmer , Peter Christian Klitgaard
IPC分类号： A61M5/32
CPC分类号： A61M5/3202 , A61M5/1452 , A61M5/20 , A61M2205/50
摘要： A drug delivery device capable of working in at least two different modes which includes a dose injection mode and a set-up mode. The drug delivery device automatically changes from the dose injection mode to the set-up mode and vice versa in accordance with the detection of the cover by a cover detection switch. In the dose injection mode doses can be set and injected; in the set-up mode various parameters assisting the use of the drug delivery device can be set. This setting is preferably done by selecting the parameters from a menu, also in this mode historical data stored in the device can be viewed.
摘要翻译：一种能够以包括剂量注射模式和建立模式的至少两种不同模式工作的药物递送装置。根据盖检测开关的检测，药物输送装置自动地从剂量注射模式改变到建立模式，反之亦然。在剂量注射模式下，可以设定和注射剂量; 在设置模式中，可以设定辅助使用药物输送装置的各种参数。该设置优选通过从菜单中选择参数来完成，而且在该模式中，可以查看存储在设备中的历史数据。

2. 发明授权

US06302869B1 Syringe having a flexible piston rod 失效
标题翻译：注射器具有柔性活塞杆
公开(公告)号：US06302869B1
公开(公告)日：2001-10-16
申请号：US08887763
申请日：1997-07-03
申请人： Peter Christian Klitgaard
发明人： Peter Christian Klitgaard
IPC分类号： A61M5315
CPC分类号： A61M5/31511 , A61M2005/31518
摘要： A flexible piston rod for use in cylinder ampoules comprises a tape shaped body (1) which is along its length provided with supporters (2; 6; 16) projecting from at least one side of the tape. The tape (1) has a width and the supporters a length so that sides of the tape and the free ends of the supporters abuts the inner wall of the ampoule (3) in at least three positions along the inner perimeter of the ampoule (3) and not all the abutment points lies on the same half of the circular cross section but are typically displaced about 120° from each other. The piston rod is moved by a gear engaging a rack (12) on the tape either on the side not carrying supporters or at the edge of the tape on the side carrying supporters.
摘要翻译：用于气瓶安瓿的柔性活塞杆包括带状体（1），其沿其长度设置有从胶带的至少一侧突出的支撑体（2; 6; 16）。带（1）具有宽度和支撑体的长度，使得带的侧面和支撑件的自由端沿着安瓿（3）的内周边的至少三个位置邻接安瓿（3）的内壁），并不是所有的邻接点都位于圆形横截面的相同的一半上，而是通常相互偏移大约120°。活塞杆通过齿轮啮合带上的齿条（12）移动，或者在不携带支撑物的一侧或在携带支撑物的一侧的带的边缘处。

3. 发明授权

US5947934A Dose display for an injection syringe 失效
标题翻译：注射器的剂量显示
公开(公告)号：US5947934A
公开(公告)日：1999-09-07
申请号：US925702
申请日：1997-09-09
申请人： Steffen Hansen , Peter Christian Klitgaard
发明人： Steffen Hansen , Peter Christian Klitgaard
IPC分类号： A61M5/31 , A61M5/315 , A61M5/00
CPC分类号： A61M5/31553 , A61M5/31525 , A61M2005/3125 , A61M2005/3126
摘要： The present invention relates to injection syringes comprising a housing accommodating an ampoule containing medicine sufficient for a number of dosed injections. The syringe has a dose setting mechanism by which doses may be set by rotating a dose setting element relative to the housing and the dose set is indicated on a scale. The scale is formed as a clock dial having a first part secured to the housing and a second part which is rotatable relative to the first part and which is coupled to the dose setting element, one of parts carries the scale and the other carries an indicating member indicating a point on the scale. The angular distance between the divisions of the scale corresponds to the minute divisions on an ordinary clock. Holes are provided along the scale which holes can receive a pin forming a stop which cannot be passed by the indicating member.
摘要翻译：注射器技术领域本发明涉及一种注射器，其包括容纳包含足以进行多次剂量注射的药物的安瓿的壳体。注射器具有剂量设定机构，通过该剂量设定机构可以通过相对于壳体旋转剂量设定元件来设定剂量，并且以刻度表示剂量设定。刻度形成为具有固定到壳体的第一部分的钟表盘和可相对于第一部分旋转的第二部分，并且其连接到剂量设定元件，部件中的一个承载标尺，而另一个承载指示成员表示一个比例点。刻度的分割之间的角距对应于普通时钟上的微分。沿着刻度设置孔，孔可以接收形成不能被指示构件通过的止挡的销。

4. 再颁专利

USRE41956E1 Dose setting limiter 有权
标题翻译：剂量设定限制器
公开(公告)号：USRE41956E1
公开(公告)日：2010-11-23
申请号：US11122211
申请日：2005-05-04
申请人： Peter Christian Klitgaard , Steffen Hansen , Bo Radmer , Claus Schmidt Moller
发明人： Peter Christian Klitgaard , Steffen Hansen , Bo Radmer , Claus Schmidt Moller
IPC分类号： A61M5/00 , A61M5/178 , A61M5/315
CPC分类号： A61M5/31585 , A61M5/24 , A61M5/31511 , A61M5/31525 , A61M5/31535 , A61M5/31541 , A61M5/31551 , A61M5/31553 , A61M5/31555 , A61M5/31568 , A61M5/31575 , A61M5/3158 , A61M2005/3125 , A61M2005/3126 , A61M2005/31518 , A61M2005/3152
摘要： A limiting mechanism which prevents the setting of a dose, which exceeds the amount of liquid left in a cartridge of an injection device, is disclosed. The injection device is the type where a dose is set by rotating a dose setting member relative to a driver and away from a fixed stop in the injection device. The dose setting member interfaces the driver such that the dose setting member can be rotated in one direction without rotating the driver. The dose is injected by rotating back the dose setting member which during the backward rotation carries the driver with it. Rotating the driver causes the piston rod to move forward inside the cartridge and expel some of the liquid contained in the cartridge. The driver is provided with a track having a length which is related to the total amount of liquid in the cartridge and which track is engaged by a track follower coupled to the dose setting member to follow rotation of this dose setting member. Each time a dose is set and injected, the track follower moves further into the track. When the track follower reaches the end of the track the dose setting member can not be rotated further, and a dose larger than the remaining liquid in the cartridge cannot be set.
摘要翻译：公开了一种限制机构，其防止剂量的设定超过注射装置的药筒中残留的液体量。注射装置是通过相对于驾驶员旋转剂量设定构件并远离注射装置中的固定止动件来设定剂量的类型。剂量设定部件使驱动器接合，使得剂量设定部件能够在一个方向上旋转而不使驾驶员旋转。通过旋转剂量设定构件来注射剂量，在剂量设定构件中，在反向旋转期间携带驾驶员。旋转驱动器使得活塞杆在筒内向前移动并排出容纳在盒中的一些液体。驱动器设置有具有与筒中的液体总量相关的长度的轨道，并且轨道由耦合到剂量设定构件的轨道从动件接合以跟随该剂量设定构件的旋转。每次设定和注入剂量时，跟踪跟随器进一步移动到轨道中。当轨道跟随器到达轨迹的末端时，剂量设定构件不能进一步旋转，并且不能设置大于盒中剩余液体的剂量。

5. 发明申请

US20090118592A1 Medical System Comprising a Sensor Device 审中-公开
标题翻译：包含传感器装置的医疗系统
公开(公告)号：US20090118592A1
公开(公告)日：2009-05-07
申请号：US12095961
申请日：2006-12-08
申请人： Peter Christian Klitgaard
发明人： Peter Christian Klitgaard
IPC分类号： A61B5/00
CPC分类号： A61M5/14276 , A61B5/002 , A61B5/14532 , A61B5/150022 , A61B5/150358 , A61B5/155 , A61B5/6849 , A61M5/14248 , A61M2005/14252 , A61M2005/14268 , A61M2005/1581 , A61M2005/1585 , A61M2205/3507 , A61M2205/3523 , A61M2205/3561 , A61M2205/3569 , A61M2205/3576 , A61M2205/52 , A61M2205/8212 , A61M2230/201
摘要： A medical system is provided comprising a sensor unit and a receiving unit is provided, the sensor unit being adapted to generate sensor data indicative of a time-dependent characteristic of a subject, and transmit data to a receiver at intervals determined by an analysis of time-dependent changes in the generated sensor data, the receiving unit being adapted to receive sensor data at a non-predetermined rate. By this arrangement sensor data can be transmitted only when considered necessary in accordance with a predetermined strategy, this reducing the energy consumption associated with the transmission of data. The strategy may set out that the transmission of sensor data is skipped in case there is no or only a small change in an actual sensor data value. On the other hand, in case of rapid changes in sensor data values, sensor data may be transmitted at higher rate.
摘要翻译：提供了包括传感器单元和接收单元的医疗系统，所述传感器单元适于产生指示对象的时间相关特性的传感器数据，并且以由时间分析确定的间隔将数据发送到接收器所产生的传感器数据的相关变化，接收单元适于以非预定速率接收传感器数据。通过这种布置，传感器数据只有在根据预定的策略被认为是必要的时才能传输，这降低了与数据传输相关联的能量消耗。该策略可以规定，在实际传感器数据值没有或仅有小的变化的情况下跳过传感器数据的传输。另一方面，在传感器数据值的快速变化的情况下，可以以更高的速率传输传感器数据。

6. 发明申请

US20080306449A1 Injection Device With Cap 有权
标题翻译：带帽的注射装置
公开(公告)号：US20080306449A1
公开(公告)日：2008-12-11
申请号：US11663185
申请日：2005-09-08
申请人： Johnny Kristensen , Jim Radmer , Peter Christian Klitgaard
发明人： Johnny Kristensen , Jim Radmer , Peter Christian Klitgaard
IPC分类号： A61M5/32 , A61M5/00
CPC分类号： A61M5/3202 , A61M5/1452 , A61M5/20 , A61M2205/50
摘要： A drug delivery device capable of working in at least two different modes which includes a dose injection mode and a set-up mode. The drug delivery device automatically changes from the dose injection mode to the set-up mode and vice versa in accordance with the detection of the cover by a cover detection switch. In the dose injection mode doses can be set and injected; in the set-up mode various parameters assisting the use of the drug delivery device can be set. This setting is preferably done by selecting the parameters from a menu, also in this mode historical data stored in the device can be viewed.
摘要翻译：一种能够以包括剂量注射模式和建立模式的至少两种不同模式工作的药物递送装置。根据盖检测开关的检测，药物输送装置自动地从剂量注射模式改变到建立模式，反之亦然。在剂量注射模式下，可以设定和注射剂量; 在设置模式中，可以设定辅助使用药物输送装置的各种参数。该设置优选通过从菜单中选择参数来完成，而且在该模式中，可以查看存储在设备中的历史数据。

7. 发明授权

US06582404B1 Dose setting limiter 有权
标题翻译：剂量设定限制器
公开(公告)号：US06582404B1
公开(公告)日：2003-06-24
申请号：US09655922
申请日：2000-09-06
申请人： Peter Christian Klitgaard , Steffen Hansen , Bo Radmer , Claus Schmidt Møller
发明人： Peter Christian Klitgaard , Steffen Hansen , Bo Radmer , Claus Schmidt Møller
IPC分类号： A61M500
CPC分类号： A61M5/31585 , A61M5/24 , A61M5/31511 , A61M5/31525 , A61M5/31535 , A61M5/31541 , A61M5/31551 , A61M5/31553 , A61M5/31555 , A61M5/31568 , A61M5/31575 , A61M5/3158 , A61M2005/3125 , A61M2005/3126 , A61M2005/31518 , A61M2005/3152
摘要： A limiting mechanism which prevents the setting of a dose, which exceeds the amount of liquid left in a cartridge of an injection device, is disclosed. The injection device is the type where a dose is set by rotating a dose setting member relative to a driver and away from a fixed stop in the injection device. The dose setting member interfaces the driver such that the dose setting member can be rotated in one direction without rotating the driver. The dose is injected by rotating back the dose setting member which during the backward rotation carries the driver with it. Rotating the driver causes the piston rod to move forward inside the cartridge and expel some of the liquid contained in the cartridge. The driver is provided with a track having a length which is related to the total amount of liquid in the cartridge and which track is engaged by a track follower coupled to the dose setting member to follow rotation of this dose setting member. Each time a dose is set and injected, the track follower moves further into the track. When the track follower reaches the end of the track the dose setting member can not be rotated further, and a dose larger than the remaining liquid in the cartridge cannot be set.
摘要翻译：公开了一种限制机构，其防止剂量的设定超过注射装置的药筒中残留的液体量。注射装置是通过相对于驾驶员旋转剂量设定构件并远离注射装置中的固定止动件来设定剂量的类型。剂量设定部件使驱动器接合，使得剂量设定部件能够在一个方向上旋转而不使驾驶员旋转。通过旋转剂量设定构件来注射剂量，在剂量设定构件中，在反向旋转期间携带驾驶员。旋转驱动器使得活塞杆在筒内向前移动并排出容纳在盒中的一些液体。驱动器设置有具有与筒中的液体总量相关的长度的轨道，并且轨道由耦合到剂量设定构件的轨道从动件接合以跟随该剂量设定构件的旋转。每次设定和注入剂量时，跟踪跟随器进一步移动到轨道中。当轨道跟随器到达轨迹的末端时，剂量设定构件不能进一步旋转，并且不能设置大于盒中剩余液体的剂量。

8. 发明授权

US06524280B2 Dose setting limiter 失效
标题翻译：剂量设定限制器
公开(公告)号：US06524280B2
公开(公告)日：2003-02-25
申请号：US09768760
申请日：2001-01-24
申请人： Steffen Hansen , Peter Christian Klitgaard
发明人： Steffen Hansen , Peter Christian Klitgaard
IPC分类号： A61M500
CPC分类号： A61M5/31525 , A61M5/31536 , A61M5/31538 , A61M5/31553 , A61M2005/3125 , A61M2005/3126 , A61M2005/3154
摘要： Described is a dose setting limiter for medical injectors of the type having a housing accommodating an ampoule-containing medicine sufficient for a number of dosed injections, a rotary dose setting knob, which is rotational relative to the housing and by which doses may be set by rotating the dose setting knob and an injection button which, when activated, administers the set dose. The dose setting limiter includes a stationary first part connected to the housing, and a second part fitted over the rotary dose setting knob, the second part being able to rotate together with the dose setting knob when setting up a dose and the second part being rotational relative to the first part. A third part is placed between the first part and the second part, the third part having means cooperating with means on the second part for limiting the dose setting.
摘要翻译：描述了一种用于医疗注射器的剂量设定限制器，其具有容纳足够多剂量注射的安瓿药物的壳体，旋转剂量设定旋钮相对于壳体旋转，并且剂量可以由旋转剂量设置旋钮和一个注射按钮，当被激活时，该按钮管理设定的剂量。剂量设定限制器包括连接到壳体的固定第一部分和装配在旋转剂量设定旋钮上的第二部分，第二部分能够在设定剂量时与剂量设定旋钮一起旋转，第二部分旋转相对于第一部分。第三部分放置在第一部分和第二部分之间，第三部分具有与第二部分上的装置配合的装置，用于限制剂量设定。

9. 发明授权

US06021824A Kit for storage and mixing of agents of which at least one is liquid 失效
标题翻译：用于储存和混合其中至少一种是液体的试剂的试剂盒
公开(公告)号：US06021824A
公开(公告)日：2000-02-08
申请号：US894641
申请日：1997-08-26
申请人： Andre Larsen , Gabriel J.o slashed.rgensen , Peter Norland Jensen , James M. Flink , Peter Christian Klitgaard
发明人： Andre Larsen , Gabriel J.o slashed.rgensen , Peter Norland Jensen , James M. Flink , Peter Christian Klitgaard
IPC分类号： A61J3/00 , A61J1/00 , A61J1/20 , B65B1/04
CPC分类号： A61J1/2089 , A61J1/201 , A61J1/2013 , A61J1/2075 , A61J1/2082
摘要： A kit for mixing comprises a housing accommodating an ampoule containing a solid and a container containing a solvent which is either pre-pressurized or which may be pressurized when it is desired to mix to the liquid and solid components. A needle unit comprises a first needle, the opposite ends of which pierce rubber membranes closing the ampoule and the container, to establish a transport channel through which pressurized solvent flows from the container to the ampoule. The ampoule is vented through a second needle inserted through the membrane of the ampoule and provided with a micro-filter. In one embodiment, the needle unit is displaceable to cause the ends of the needles to pierce the respective membranes, and locked in place by a spring biased locking mechanism. A branch passage from the needle is connected to a cylinder containing a piston coupled to the locking mechanism. When the ampoule is full, pressure in the branch passage will rise, actuating the piston and releasing the locking mechanism. In an alternative embodiment, the needle mechanism is stationary, and the ampoule and container are moved into engagement with the respective needle ends.
摘要翻译： PCT No.PCT / DK96 / 00085 Sec。 371日期：1997年8月26日 102（e）日期1997年8月26日PCT提交1996年2月29日PCT公布。公开号WO96 / 26702 日期1996年9月6日用于混合的试剂盒包括容纳包含固体的容器和容纳含有预加压溶剂的容器的壳体，或者当需要与液体和固体组分混合时可以加压。针单元包括第一针，其相对端刺穿关闭安瓿和容器的橡胶膜，以建立输送通道，加压溶剂通过该输送通道从容器流到安瓿。安瓿通过穿过安瓿的膜的第二针排出，并设置有微滤器。在一个实施例中，针单元可移动以使针的端部刺穿相应的膜，并且通过弹簧偏置的锁定机构锁定就位。来自针的分支通道连接到包含联接到锁定机构的活塞的气缸。当安瓿充满时，分支通道中的压力将升高，致动活塞并释放锁定机构。在替代实施例中，针机构是静止的，并且安瓿和容器被移动成与相应的针端接合。

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