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1. 发明申请

WO2008128775A2 STABILISED PHARMACEUTICAL COMPOSITION CONTAINING PREGABALINE 审中-公开
标题翻译：含有PREGABALINE的稳定化学药物组合物
公开(公告)号：WO2008128775A2
公开(公告)日：2008-10-30
申请号：PCT/EP2008003285
申请日：2008-04-23
申请人： RATIOPHARM GMBH , SCHULZE-NAHRUP JULIA , LEHMANN ALEXANDER , MUSKUELUS FRANK
发明人： SCHULZE-NAHRUP JULIA , LEHMANN ALEXANDER , MUSKUELUS FRANK
CPC分类号： A61K9/2009 , A61K9/0095 , A61K9/1623 , A61K9/2846 , A61K31/197
摘要： Solid pharmaceutical composition containing: (a) pregabaline as active principle and (b) one or several pharmaceutical auxiliary agents, the composition being essentially free from saccharides and comprising no further amino acids, apart from pregabaline.
摘要翻译：固体药物组合物，其含有：（a）作为活性成分的pregabaline和（b）一种或几种药物辅助剂，所述组合物基本上不含糖，除了普瑞巴拉之外不包含其它氨基酸。

2. 发明专利

GB190515936A An Improved Rotary Internal Combustion Engine. 未知
公开(公告)号：GB190515936A
公开(公告)日：1906-11-03
申请号：GB190515936D
申请日：1905-08-03
申请人： LEHMANN ALEXANDER
发明人： LEHMANN ALEXANDER
摘要： 15,936. Lehmann, A. Aug. 3. Gas and like engines, rotary. A revolving- cylinder engine has its cylinders in co-axial pairs on opposite sides of the crank-shaft, the piston - rods being attached to a transverselyslotted yoke b in which the crank-shaft c works ; the slot b in the yoke is not quite at right-angles to the cylinder axis, so that the pistons dwell at the end of their strokes. The engines work on a two-stroke cycle, a charge being drawn through the crank-shaft and port i into the space k, whence it is forced through a chamber l, passages m, n, and ports o into the cylinder and expels the exhaust through ports u which alternate with the ports o. A flange on the head of the piston is notched to uncover the ports o, and the ports p between the notches have grooves p to direct the incoming charge over the cylinder walls. The chambers k are separated from the crank chamber d, which is fitted with stuffing-boxes g and is supplied with oil up to the level of the overflow pipe t through passages q, r, s. Some oil enters the charge inlet i through the pipe t. The frame turns about the crank-shaft on roller bearings as shown.

3. 发明专利

GB190400125A An Improved Rotary Internal Combustion Engines. 未知
公开(公告)号：GB190400125A
公开(公告)日：1904-12-01
申请号：GB190400125D
申请日：1904-01-02
申请人： ZINGEL GUSTAVUS MARTIN , LEHMANN ALEXANDER
发明人： ZINGEL GUSTAVUS MARTIN , LEHMANN ALEXANDER
摘要： 125. Zingel, G. M., and Lehmann, A. Jan. 2. Revolving-cylinder type.-An internal-combustion engine has two or more cylinders revolving about a fixed axis. The framework carrying the cylinders carries also exhaust silencers and coolers and serves as a flywheel, and in some cases as a driving-wheel. The cylinders A', A , Fig. 1, are formed in one with a central chamber C. Fig. 5 shows an axial section of the central chamber C. The central shaft B is not continuous, and its two parts carry recessed discs B at their ends on which the casing C runs on ball bearings. Escape of fluid is prevented by plates E', E , spring pressed against flanges e', e . The chamber C is divided into three compartments C , C , C by two discs F', F , which are held against an internal flange F in the chamber by a screw with a spring washer. The fixed eccentric or crank-pin h passes through the chamber C, and the connecting-rods g are arranged on opposite sides of the discs F , F'. The explosive mixture enters the space C between the discs F , F , through the hollow crank-pin h, and escapes to the chambers C , C . In order to effect the distribution, the periphery of each disc F , F is cut away at one place, and the flange F is correspondingly bevelled. The gases issue in a thin sheet, and are thus thoroughly mixed. The discs F , F' may be made thin and flexible and may be circularly corrugated, in order to yield and admit gas to the chambers C , C when their pressures fall below that in the chamber C . After compression by the descending piston the gases pass by passages k , k , Fig. 1, to ports in the cylinders. A guard m on the piston deflects the charge upwards, and prevents mixture with the exhaust, which escapes by a port L' and pipe o' to one of two semicircular cylindrical chambers P' forming the periphery of the framework. Each chamber P is divided into several compartments by partitions q . Compartments are connected by thin metal casings secured to the exteriors of the chambers P and perforations r. The gases escape at the end of each chamber P through perforations.

4. 发明专利

GB191315857A Improvements in and relating to Ironing and Glazing Machines. 未知
公开(公告)号：GB191315857A
公开(公告)日：1913-08-19
申请号：GB191315857D
申请日：1912-08-19
申请人： LEHMANN ALEXANDER
发明人： LEHMANN ALEXANDER
IPC分类号： D06F71/22
摘要： 15,857. Lehmann, A. Aug. 19, 1912. Ironing-machines specially constructed for treating collars.-A form for use in shaping and ironing Eton and similar collars comprises a cylindrical inner portion a for the neck-band and a conical outer portion a suited to the particular shape of collar under treatment. A gap is provided to receive the tabs of the collar. The form may be detachably mounted on a base by means of fixed pins b adapted to engage slots at the front of the form and by a clamping-lever b engaging a lug a at the rear of the form. The form is especially suitable for use with the collar shaping and ironing machine described in Specification 18,986/12.

5. 发明专利

GB191322422A Improvements in and relating to Ironing Machines. 未知
公开(公告)号：GB191322422A
公开(公告)日：1914-10-05
申请号：GB191322422D
申请日：1913-10-04
申请人： LEHMANN ALEXANDER
发明人： LEHMANN ALEXANDER
IPC分类号： D06F71/26
摘要： 22,422. Lehmann, A. Oct. 4. No Patent granted (Sealing fee not paid). Ironing-machines with roller and stationary iron. -The necks or collar-bands and yokes of shirts are ironed by placing them in position upon a partly felt-covered former a, a mounted upon a rotating shaft b driven by means of screw gearing e with pedal-operated belt-shifting gear, the former being heated internally by means of a gas burner a . After the work is in position, an iron h, shaped to correspond with the former, is forced against it and is kept stationary in the pressing position during ironing. The iron is heated internally, air and gas being supplied through the hollow arm h that supports it, and the necessary movement is obtained by means of a handle k carrying a camplate grooved to engage the teeth of a wheel h secured to the arm and pivoted upon a spindle j . A stationary guard g, constructed of any suitable fabric and supported upon the spindle b, prevent entanglement of the sbirt with the mechanism. According to the Provisional Specification, the front of the shirt is carried by a wire guard to ensure the shirt remaining in position ; the handle for moving the pressing-iron may also operate by means of teeth thereon.

6. 发明申请

WO2008128775A3 STABILISED PHARMACEUTICAL COMPOSITION CONTAINING PREGABALINE 审中-公开
公开(公告)号：WO2008128775A3
公开(公告)日：2008-10-30
申请号：PCT/EP2008/003285
申请日：2008-04-23
申请人： RATIOPHARM GMBH , SCHULZE-NAHRUP, Julia , LEHMANN, Alexander , MUSKÜLUS, Frank
发明人： SCHULZE-NAHRUP, Julia , LEHMANN, Alexander , MUSKÜLUS, Frank
IPC分类号： A61K9/16
摘要： Solid pharmaceutical composition containing: (a) pregabaline as active principle and (b) one or several pharmaceutical auxiliary agents, the composition being essentially free from saccharides and comprising no further amino acids, apart from pregabaline.

7. 发明专利

GB191218986A Improvements in and relating to Ironing and Glazing Machines and the like. 未知
公开(公告)号：GB191218986A
公开(公告)日：1913-08-19
申请号：GB191218986D
申请日：1912-08-19
申请人： LEHMANN ALEXANDER
发明人： LEHMANN ALEXANDER
IPC分类号： D06F71/22
摘要： 18,986. Lehmann, A. Aug. 19. Ironing-machines specially constructed for treating collars and cuffs.-Eton, polo, and other turn-down collars are shaped on a form by means of two ironing-heads one of which irons the fold and the other the neck-band. The collar form a is removably mounted on a base b and is preferably of the construction described in Specification 15,857/13. The bead g for ironing the fold is slidably and rotatably mounted on an arm f carried on a standard c, and is provided with two grooves l. The head h for ironing the neck-band against the felt-covered flange a isslidably mounted on a second arm f and is raised and lowered by a lever k. Gas is supplied to the heads through the holiow standard and arms.

8. 发明专利

GB190712368A Improvements in and relating to Electric Amperemeters Voltmeters and the like. 未知
公开(公告)号：GB190712368A
公开(公告)日：1908-05-21
申请号：GB190712368D
申请日：1907-05-28
申请人： LEHMANN ALEXANDER
发明人： LEHMANN ALEXANDER
摘要： 12,368. Lehmann, A. May 28. Current meters.-A lowreading ammeter or voltmeter for testing secondary batteries has a long tapering coil c wound on a bobbin b in which moves a mild-steel plunger f, controlled by a spring y connected to an adjustable set - screw i. The bobbin is fixed inside a metal casing a, which is connected to one end of the coil and forms one terminal of the instrument, the other end of the coil passing out through an ebonite plug j and cover j . A pointer k is attached to the plunger and moves over a vertical scale. Two pointers may be used so as to balance the plunger. In a volt-meter, a few turns are added to the lower part of the coil, so as to prevent the sensitiveness of the instrument from falling off too rapidly. In a combined ammeter and voltmeter, two coils are wound on the same bobbin. Energy meters.-A watt-meter of this type may have two tapered coils.

9. 发明申请

WO2008131961A1 HERSTELLUNGSVERFAHREN FÜR ADSORBATE EINES RASAGILINSALZES MIT EINEM WASSERLÖSLICHEN HILFSSTOFF 审中-公开
标题翻译：用于生产吸附法用水溶性辅助物质RASAGILINSALZES
公开(公告)号：WO2008131961A1
公开(公告)日：2008-11-06
申请号：PCT/EP2008/003498
申请日：2008-04-30
申请人： RATIOPHARM GMBH , LEHMANN, Alexander , MUSKULUS, Frank , SCHULZE NAHRUP, Julia
发明人： LEHMANN, Alexander , MUSKULUS, Frank , SCHULZE NAHRUP, Julia
IPC分类号： A61K9/16 , A61K31/00 , A61K9/20
CPC分类号： A61K47/48176 , A61K9/1629 , A61K9/1635 , A61K9/1652 , A61K9/1694 , A61K9/2054 , A61K9/2059 , A61K9/2095 , A61K31/135 , A61K47/542 , A61K47/58 , A61K47/61
摘要： Die Erfindung betrifft ein Adsorbat eines pharmazeutisch verträglichen Salzes des Rasagilins mit zumindest einem pharmazeutisch verträglichen Hilfsstoff, wobei der zumindest eine pharmazeutisch verträgliche Hilfsstoff ein wasserlöslicher, organischer Hilfsstoff ist und das Salz des Rasagilins in dem Adsorbat als amorphe Substanz vorliegt.
摘要翻译：本发明涉及的雷沙吉兰与至少一种可药用赋形剂，其中所述至少一种可药用赋形剂是一种水溶性有机辅助材料和盐的存在雷沙吉兰的吸附物，为无定形物质的药学上可接受的盐的吸附物。

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