专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08882748B2 Transmucosal drug delivery device and method including chemical permeation enhancers 有权
标题翻译：粘膜下药物递送装置和方法包括化学渗透促进剂
公开(公告)号：US08882748B2
公开(公告)日：2014-11-11
申请号：US12576087
申请日：2009-10-08
申请人： Scott Uhland , Eric Peeters , Hussain Fatakdawala
发明人： Scott Uhland , Eric Peeters , Hussain Fatakdawala
IPC分类号： A61K9/22 , A61M31/00 , A61K9/00
CPC分类号： A61M31/002 , A61K9/0036
摘要： Devices and methods are provided for transmucosal drug delivery. The transmucosal drug delivery device may include a housing configured for intralumenal deployment, such as intravaginally, into a human or animal subject; a drug-dispensing portion which contains at least one drug, the drug-dispensing portion being configured to dispense the drug from the housing by positive displacement; and a permeability enhancer-dispensing portion configured to release or generate a permeability enhancing substance to disrupt at least one region of a mucosal barrier adjacent to the housing at a selected time while intralumenally deployed in the human or animal subject. The device may be operable to dispense the drug from the housing to a region of the mucosal barrier disrupted by the permeability enhancing substance.
摘要翻译：提供了用于经粘膜药物递送的装置和方法。透粘膜药物递送装置可以包括构造成用于腔内部署的壳体，例如阴道内部分入人或动物受试者; 药物分配部分，其包含至少一种药物，所述药物分配部分构造成通过正位移从所述壳体分配药物; 以及渗透性增强剂分配部分，被配置为释放或产生渗透性增强物质，以在选择的时间在脉管内部署在人或动物受试者中的同时破坏邻近所述壳体的粘膜屏障的至少一个区域。该装置可操作以将药物从壳体分配到由渗透性增强物质破坏的粘膜屏障的区域。

2. 发明申请

US20110087192A1 TRANSMUCOSAL DRUG DELIVERY DEVICE AND METHOD INCLUDING CHEMICAL PERMEATION ENHANCERS 有权
标题翻译：转运药物递送装置及包括化学渗透增强剂的方法
公开(公告)号：US20110087192A1
公开(公告)日：2011-04-14
申请号：US12576087
申请日：2009-10-08
申请人： Scott Uhland , Eric Peeters , Hussain Fatakdawala
发明人： Scott Uhland , Eric Peeters , Hussain Fatakdawala
IPC分类号： A61M31/00 , A61K33/40 , A61K38/02 , A61K31/045 , A61K31/19 , A61K31/23 , A61K38/46 , A61K31/519 , A61K31/52
CPC分类号： A61M31/002 , A61K9/0036
摘要： Devices and methods are provided for transmucosal drug delivery. The transmucosal drug delivery device may include a housing configured for intralumenal deployment, such as intravaginally, into a human or animal subject; a drug-dispensing portion which contains at least one drug, the drug-dispensing portion being configured to dispense the drug from the housing by positive displacement; and a permeability enhancer-dispensing portion configured to release or generate a permeability enhancing substance to disrupt at least one region of a mucosal barrier adjacent to the housing at a selected time while intralumenally deployed in the human or animal subject. The device may be operable to dispense the drug from the housing to a region of the mucosal barrier disrupted by the permeability enhancing substance.
摘要翻译：提供了用于经粘膜药物递送的装置和方法。透粘膜药物递送装置可以包括构造成用于腔内部署的壳体，例如阴道内部分入人或动物受试者; 药物分配部分，其包含至少一种药物，所述药物分配部分构造成通过正位移从所述壳体分配药物; 以及渗透性增强剂分配部分，被配置为释放或产生渗透性增强物质，以在选择的时间在脉管内部署在人或动物受试者中的同时破坏邻近所述壳体的粘膜屏障的至少一个区域。该装置可操作以将药物从壳体分配到由渗透性增强物质破坏的粘膜屏障的区域。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式