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1. 发明申请

WO2009055725A1 MECHANICAL ARM 审中-公开
标题翻译：机械臂
公开(公告)号：WO2009055725A1
公开(公告)日：2009-04-30
申请号：PCT/US2008/081196
申请日：2008-10-24
申请人： LIPOSONIX, INC. , BOCKENSTEDT, Craig, Robert , HORTH, Roland
发明人： BOCKENSTEDT, Craig, Robert , HORTH, Roland
IPC分类号： A61N7/02
CPC分类号： A61N7/02 , A61B2017/00477
摘要： An interchangeable transducer for use with an ultrasound medical system having a keyless adaptor and capable of operating in a wet environment. The interchangeable transducer has an adaptor for engaging a medical system, an ultrasound transducer and additional electronics to provide a self-contained insert for easy replacement and usage in a variety of medical applications. A slip ring spacer is also disclosed, the slip ring spacer for use with a pancake slip ring having a base and flange configuration to form one or more channels around each contact ring of the pancake slip ring. The channels provide fluid isolation around each connector to help reduce electronic cross talk and contact corrosion between the connector pads of the slip ring while the slip ring is immersed in a wet environment.
摘要翻译：一种用于具有无钥匙适配器并能够在潮湿环境中操作的超声波医疗系统的可互换传感器。可互换换能器具有用于接合医疗系统的适配器，超声换能器和附加电子装置，以提供一种独立的插入件，以便于在各种医疗应用中的更换和使用。还公开了一种滑环隔片，该滑环间隔件用于具有基部和凸缘构造的薄饼滑环，以在薄饼滑环的每个接触环周围形成一个或多个通道。通道在每个连接器周围提供流体隔离，有助于减少滑环的连接垫之间的电子串扰和接触腐蚀，同时滑环浸入湿环境中。

2. 发明申请

WO2012024545A3 HIFU APPLICATOR 审中-公开
标题翻译： HIFU申请人
公开(公告)号：WO2012024545A3
公开(公告)日：2012-05-31
申请号：PCT/US2011048331
申请日：2011-08-18
申请人： ALBRIGHT ETHAN P , HORTH ROLAND , MURKOWSKI JOHN , BROWN TROY , PHILLIPS DANIEL B , DARLINGTON GREGORY P , SMITH ADAM L , THIELMAN SCOTT C , STANCIK BLAKE R , MIRABILIS MEDICA INC
发明人： ALBRIGHT ETHAN P , HORTH ROLAND , MURKOWSKI JOHN , BROWN TROY , PHILLIPS DANIEL B , DARLINGTON GREGORY P , SMITH ADAM L , THIELMAN SCOTT C , STANCIK BLAKE R
IPC分类号： A61N7/00 , A61B18/00 , A61N7/02
CPC分类号： A61N7/02 , A61B8/00 , A61B8/429 , A61B8/4461 , A61B2090/378 , A61N2007/0091 , G10K11/355
摘要： An applicator for providing HIFU therapy to a patient includes a HIFU transducer that is rotatably coupled to a frame. In one embodiment, the rotatable coupling is configured such that the HIFU transducer can be mechanically oriented to position a focal zone of the HIFU transducer at any desired location in a treatment volume radially outward from a longitudinal axis of the applicator while the HIFU transducer remains within a housing that is not more than a defined percentage (e.g., 50%) larger than the maximum diameter of the HIFU transducer. In one embodiment, the HIFU transducer is rotatably coupled to the frame with a ball and socket joint. In another embodiment, the HIFU transducer is rotatably coupled to the frame with an offset gimble assembly. A pair of linear actuators and drive shafts engage the HIFU transducer to orient HIFU transducer in a desired direction.
摘要翻译：用于向患者提供HIFU治疗的施用器包括可旋转地联接到框架的HIFU换能器。在一个实施例中，可旋转联接器被配置成使得HIFU换能器能够被机械地取向，以将HIFU换能器的聚焦区域定位在治疗体积处于治疗体积的任何期望位置，处理体积从施加器的纵向轴线向外放置，同时HIFU换能器保持在一个不超过HIFU换能器最大直径的定义百分比（例如，50％）的外壳。在一个实施例中，HIFU换能器可旋转地联接到具有球窝接头的框架。在另一个实施例中，HIFU换能器可旋转地联接到具有偏移灵活组件的框架上。一对线性致动器和驱动轴接合HIFU传感器，以将HIFU换能器定向到所需的方向。

3. 发明申请

WO2011123862A3 OFFICE-BASED SYSTEM FOR TREATING UTERINE FIBROIDS OR OTHER TISSUES WITH HIFU 审中-公开
标题翻译：用于治疗子宫纤维蛋白或其他与HIFU的组织的基于办公室的系统
公开(公告)号：WO2011123862A3
公开(公告)日：2012-03-08
申请号：PCT/US2011031129
申请日：2011-04-04
申请人： MIRABILIS MEDICA INC , DARLINGTON GREGORY P , CONNOLLY MICHAEL J , REED JUSTIN A , PARSONS JESSICA E , HORTH ROLAND , MURKOWSKI JOHN , EMERY CHARLES D
发明人： DARLINGTON GREGORY P , CONNOLLY MICHAEL J , REED JUSTIN A , PARSONS JESSICA E , HORTH ROLAND , MURKOWSKI JOHN , EMERY CHARLES D
IPC分类号： A61N7/00 , A61B18/00
CPC分类号： A61N7/02 , A61B2017/00172 , A61B2090/378 , A61N2007/0065 , A61N2007/0082 , A61N2007/0091 , A61N2007/0095
摘要： A method for treating a desired volume of tissue using HIFU or other energy modality to ablate a pattern of elemental treatment volumes each having a volume that is greater than that of the focal zone of the HIFU transducer but smaller than the overall volume of the desired treatment volume. In one embodiment, the pattern of elemental treatment volumes are arranged to form a shell which partially or wholly encapsulates the desired volume of tissue, which then necroses in situ due to effects other than direct HIFU damage (including some combination of ischemia, thermal conduction, inflammation, apoptosis, etc.). The necrosed tissue remains in the body and is subsequently resorbed and/or healed via normal body mechanisms.
摘要翻译：一种使用HIFU或其他能量模式来治疗期望体积的组织的方法，以消融每个具有大于HIFU换能器的焦点区域的体积的体积的元素处理体积的图案，但小于所需治疗的总体积卷。在一个实施方案中，元件处理体积的图案被布置成形成部分地或完全地包封所需体积的组织的壳，其由于除了直接HIFU损伤之外的作用（包括局部缺血，热传导，炎症，凋亡等）。坏死的组织保留在体内，随后通过正常的身体机制吸收和/或愈合。

4. 发明申请

WO2011123862A2 OFFICE-BASED SYSTEM FOR TREATING UTERINE FIBROIDS OR OTHER TISSUES WITH HIFU 审中-公开
标题翻译：用于治疗子宫纤维蛋白或其他与HIFU的组织的基于办公室的系统
公开(公告)号：WO2011123862A2
公开(公告)日：2011-10-06
申请号：PCT/US2011/031129
申请日：2011-04-04
申请人： MIRABILIS MEDICA, INC. , DARLINGTON, Gregory P. , CONNOLLY, Michael J. , REED, Justin A. , PARSONS, Jessica E. , HORTH, Roland , MURKOWSKI, John , EMERY, Charles D.
发明人： DARLINGTON, Gregory P. , CONNOLLY, Michael J. , REED, Justin A. , PARSONS, Jessica E. , HORTH, Roland , MURKOWSKI, John , EMERY, Charles D.
IPC分类号： A61N7/00 , A61B18/00
CPC分类号： A61N7/02 , A61B2017/00172 , A61B2090/378 , A61N2007/0065 , A61N2007/0082 , A61N2007/0091 , A61N2007/0095
摘要： A method for treating a desired volume of tissue using HIFU or other energy modality to ablate a pattern of elemental treatment volumes each having a volume that is greater than that of the focal zone of the HIFU transducer but smaller than the overall volume of the desired treatment volume. In one embodiment, the pattern of elemental treatment volumes are arranged to form a shell which partially or wholly encapsulates the desired volume of tissue, which then necroses in situ due to effects other than direct HIFU damage (including some combination of ischemia, thermal conduction, inflammation, apoptosis, etc.). The necrosed tissue remains in the body and is subsequently resorbed and/or healed via normal body mechanisms.
摘要翻译：一种使用HIFU或其他能量模式来治疗期望体积的组织的方法，以消融每个具有大于HIFU换能器的焦点区域的体积的体积的元素处理体积的图案，但小于所需治疗的总体积卷。在一个实施方案中，元件处理体积的图案被布置成形成部分地或完全地包封所需体积的组织的壳，其由于除了直接HIFU损伤之外的作用（包括局部缺血，热传导，炎症，凋亡等）。坏死的组织保留在体内，随后通过正常的身体机制吸收和/或愈合。

5. 发明申请

WO2010040140A8 METHOD AND APPARATUS FOR TREATING TISSUES WITH HIFU 审中-公开
公开(公告)号：WO2010040140A8
公开(公告)日：2010-04-08
申请号：PCT/US2009/059589
申请日：2009-10-05
申请人： MIRABILIS MEDICA, INC. , DARLINGTON, Gregory, P. , CONNOLLY, Michael, J. , REED, Justin, A. , PARSONS, Jessica, E. , HORTH, Roland , MURKOWSKI, John
发明人： DARLINGTON, Gregory, P. , CONNOLLY, Michael, J. , REED, Justin, A. , PARSONS, Jessica, E. , HORTH, Roland , MURKOWSKI, John
IPC分类号： A61N7/00 , A61B18/00 , A61N7/02
摘要： A method for treating a desired volume of tissue using HIFU or other energy modality to ablate a pattern of elemental treatment volumes each having a volume that is greater than that of the focal zone of the HIFU transducer but smaller than the overall volume of the desired treatment volume. In one embodiment, the pattern of elemental treatment volumes are arranged to form a shell which partially or wholly encapsulates the desired volume of tissue, which then necroses in situ due to effects other than direct HIFU damage (including some combination of ischemia, thermal conduction, inflammation, apoptosis, etc.). The necrosed tissue remains in the body and is subsequently resorbed and/or healed via normal body mechanisms.

6. 发明申请

WO2012024545A2 HIFU APPLICATOR 审中-公开
标题翻译： HIFU应用程序
公开(公告)号：WO2012024545A2
公开(公告)日：2012-02-23
申请号：PCT/US2011/048331
申请日：2011-08-18
申请人： ALBRIGHT, Ethan, P. , HORTH, Roland , MURKOWSKI, John , BROWN, Troy , PHILLIPS, Daniel, B. , DARLINGTON, Gregory, P. , SMITH, Adam, L. , THIELMAN, Scott, C. , STANCIK, Blake, R. , MIRABILIS MEDICA INC.
发明人： ALBRIGHT, Ethan, P. , HORTH, Roland , MURKOWSKI, John , BROWN, Troy , PHILLIPS, Daniel, B. , DARLINGTON, Gregory, P. , SMITH, Adam, L. , THIELMAN, Scott, C. , STANCIK, Blake, R.
IPC分类号： A61N7/00 , A61B18/00 , A61N7/02
CPC分类号： A61N7/02 , A61B8/00 , A61B8/429 , A61B8/4461 , A61B2090/378 , A61N2007/0091 , G10K11/355
摘要： An applicator for providing HIFU therapy to a patient includes a HIFU transducer that is rotatably coupled to a frame. In one embodiment, the rotatable coupling is configured such that the HIFU transducer can be mechanically oriented to position a focal zone of the HIFU transducer at any desired location in a treatment volume radially outward from a longitudinal axis of the applicator while the HIFU transducer remains within a housing that is not more than a defined percentage (e.g., 50%) larger than the maximum diameter of the HIFU transducer. In one embodiment, the HIFU transducer is rotatably coupled to the frame with a ball and socket joint. In another embodiment, the HIFU transducer is rotatably coupled to the frame with an offset gimble assembly. A pair of linear actuators and drive shafts engage the HIFU transducer to orient HIFU transducer in a desired direction.
摘要翻译：用于向患者提供HIFU治疗的施放器包括可旋转地连接到框架的HIFU换能器。在一个实施例中，可旋转联接器被构造成使得HIFU换能器可以被机械地定向以将HIFU换能器的焦点区域定位在治疗区域中的任何期望位置处，其中HIFU换能器保持在距离施加器的纵向轴线径向向外外壳不超过HIFU换能器的最大直径的限定百分比（例如，50％）。在一个实施例中，HIFU换能器通过球窝关节可旋转地联接到框架。在另一个实施例中，HIFU换能器通过偏移的顶杆组件可旋转地连接到框架。一对线性致动器和驱动轴接合HIFU换能器以使HIFU换能器朝向期望的方向。

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