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1. 发明申请

WO2007002580A2 DETECTION DEVICE AND METHODS ASSOCIATED THEREWITH 审中-公开
标题翻译：检测装置及其相关方法
公开(公告)号：WO2007002580A2
公开(公告)日：2007-01-04
申请号：PCT/US2006/024791
申请日：2006-06-23
申请人： BIOVERIS CORPORATION , KOCHAR, Manish Swarnaraj , DAVIS, Charles Quentin , LELAND, Jonathan K. , MANTEUFFEL, Richard , COOK, Richard A.
发明人： KOCHAR, Manish Swarnaraj , DAVIS, Charles Quentin , LELAND, Jonathan K. , MANTEUFFEL, Richard , COOK, Richard A.
IPC分类号： G01N35/00 , G01N21/76 , G01N33/58
CPC分类号： G01N21/76 , B01L3/5082 , B01L2200/025 , B01L2300/0858 , G01N33/54326 , G01N33/5438 , G01N35/00 , G01N2035/0436 , G01N2035/0493 , G01N2035/1025
摘要： Detection devices and methods associated therewith are provided. In some embodiments, the detection system can be adapted to measure one or more analytes of interest possibly present in a sample through the use of binding reactions.
摘要翻译：提供与其相关联的检测装置和方法。在一些实施方案中，检测系统可以适于通过使用结合反应来测量样品中可能存在的一种或多种感兴趣的分析物。

2. 发明申请

WO2005114175A3 DETECTION DEVICE, COMPONENTS OF A DETECTION DEVICE, AND METHODS ASSOCIATED THEREWITH 审中-公开
标题翻译：检测装置，检测装置的部件及其相关方法
公开(公告)号：WO2005114175A3
公开(公告)日：2006-02-02
申请号：PCT/US2005014105
申请日：2005-04-26
申请人： BIOVERIS CORP , DAVIS CHARLES QUENTIN , COOK RICHARD , MATIKYAN ROBER KIRKOR , KOCHAR MANISH SWARNARAJ , HARLEY JASON CHARLES , MILLER JONATHAN MATTHEW , DANIELS JEFFREY ARTHUR
发明人： DAVIS CHARLES QUENTIN , COOK RICHARD , MATIKYAN ROBER KIRKOR , KOCHAR MANISH SWARNARAJ , HARLEY JASON CHARLES , MILLER JONATHAN MATTHEW , DANIELS JEFFREY ARTHUR
IPC分类号： G01N35/02 , B01L9/00 , G01N35/04
CPC分类号： G01N35/028 , G01N2035/042
摘要： A detection system may include a moveable tray configured to hold a multi-cell container of one or more reagents and/or one or more samples. A driving mechanism may be configured to reciprocate the tray in the first linear direction to agitate contents of the container, and may be configured to conduct electrochemiluminescence or other measurements on samples located in the container. The system may include an apparatus for retaining a container, a device for detecting the presence of a container, an apparatus for training a probe to locate and aspirate one or more reagents and/or one or more samples, a latching mechanism for moving parts in the system, and/or a positive displacement pump. A controller may be configured to control linear reciprocation of the tray to have one of a piecewise constant velocity profile and piecewise constant acceleration profile in which the number of piecewise constants does not exceed 24.
摘要翻译：检测系统可以包括配置成容纳一个或多个试剂和/或一个或多个样品的多细胞容器的可移动托盘。驱动机构可以被配置为使托盘沿第一线性方向往复移动以搅拌容器的内容物，并且可以被配置为对位于容器中的样品进行电化学发光或其它测量。该系统可以包括用于保持容器的装置，用于检测容器的存在的装置，用于训练探针以定位和吸出一个或多个试剂和/或一个或多个样品的装置，用于将部件移动系统和/或容积式泵。控制器可以被配置为控制托盘的线性往复运动以具有分段恒定速度分布和分段恒定加速度分布之一，其中分段常数的数量不超过24。

3. 发明申请

WO2007002579A3 ASSAY CARTRIDGES AND METHODS FOR POINT OF CARE INSTRUMENTS 审中-公开
标题翻译：测量仪器和点心仪器的方法
公开(公告)号：WO2007002579A3
公开(公告)日：2009-09-17
申请号：PCT/US2006024790
申请日：2006-06-23
申请人： BIOVERIS CORP , DAVIS CHARLES QUENTIN , LILJESTRAND JOHN , LELAND JONATHAN , BLANKFARD MARTIN , MILLER JONATHAN M
发明人： DAVIS CHARLES QUENTIN , LILJESTRAND JOHN , LELAND JONATHAN , BLANKFARD MARTIN , MILLER JONATHAN M
IPC分类号： A61B5/151 , A61B5/157 , B01L3/00 , C12M1/12 , G01N33/49 , G01N33/50 , G01N33/53 , G01N33/543 , G01N33/58
CPC分类号： G01N33/582 , A61B5/14546 , A61B5/150022 , A61B5/150213 , A61B5/150221 , A61B5/150229 , A61B5/150251 , A61B5/150358 , A61B5/150389 , A61B5/150503 , A61B5/150755 , A61B5/150786 , A61B5/150793 , A61B5/150862 , A61B5/15087 , A61B5/150893 , A61B5/15107 , A61B5/15117 , A61B5/15142 , A61B5/157 , A61B5/411 , B01L3/502715 , B01L3/502723 , B01L3/502738 , B01L3/502753 , B01L3/502761 , B01L3/502776 , B01L7/00 , B01L9/527 , B01L2200/027 , B01L2200/0636 , B01L2200/0647 , B01L2200/0668 , B01L2200/10 , B01L2300/022 , B01L2300/0627 , B01L2300/0645 , B01L2300/0681 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2300/0874 , B01L2300/1805 , B01L2300/1861 , B01L2300/1877 , B01L2400/0406 , B01L2400/0442 , B01L2400/046 , B01L2400/0481 , B01L2400/0487 , B01L2400/0633 , B01L2400/0677 , B01L2400/0683 , B01L2400/0688 , G01N21/6428 , G01N21/648 , G01N21/8483 , G01N33/5002 , G01N33/5302 , G01N33/54326 , G01N33/54346 , G01N33/54386 , G01N35/0098 , G01N2035/00108
摘要： Devices and methods are provided for performing a test to detect and/or quantify the presence of an analyte of interest within a sample using a portable instrument.
摘要翻译：提供了装置和方法，用于使用便携式仪器进行测试以检测和/或定量样品内感兴趣的分析物的存在。

4. 发明申请

WO2007127490A3 SYSTEMS AND METHODS FOR OBTAINING, STORING, PROCESSING AND UTILIZING IMMUNOLOGIC AND OTHER INFORMATION OF AN INDIVIDUAL OR POPULATION 审中-公开
公开(公告)号：WO2007127490A3
公开(公告)日：2007-11-08
申请号：PCT/US2007/010576
申请日：2007-04-27
申请人： BIOVERIS CORPORATION , MICHON, Francis , MOORE, Samuel, L. , FUSCO, Peter, C. , WOHLSTADTER, Samuel, J. , DAVIS, Charles, Quentin , COLEMAN, David , SHETTY, Suraj , TRAPATHI, Vinay , JOSHI, Kamini
发明人： MICHON, Francis , MOORE, Samuel, L. , FUSCO, Peter, C. , WOHLSTADTER, Samuel, J. , DAVIS, Charles, Quentin , COLEMAN, David , SHETTY, Suraj , TRAPATHI, Vinay , JOSHI, Kamini
IPC分类号： G06Q50/00
摘要： A system and method for assessing the immunological status of one or more individuals in a patient population is presented. The method includes establishing a database comprising a plurality of records of information each representative of the immune status of an individual in the population, each of said records including (1 ) current information from one or more assays for the presence of a biochemical, and (2) individual specific information comprising one or more of said individual's medical history, said individual's doctors; observations and historical, demographic, lifestyle, and familial information relating to said individual. The method further includes processing the information in said database to find trends or patterns relating to the. immune status of individuals in said patient population; and using the said trends or patterns as part of a health care related decision making process.

5. 发明申请

WO2007127490A2 SYSTEMS AND METHODS FOR OBTAINING, STORING, PROCESSING AND UTILIZING IMMUNOLOGIC AND OTHER INFORMATION OF AN INDIVIDUAL OR POPULATION 审中-公开
标题翻译：用于获取，存储，处理和使用个体或人口的免疫和其他信息的系统和方法
公开(公告)号：WO2007127490A2
公开(公告)日：2007-11-08
申请号：PCT/US2007010576
申请日：2007-04-27
申请人： BIOVERIS CORP , MICHON FRANCIS , MOORE SAMUEL L , FUSCO PETER C , WOHLSTADTER SAMUEL J , DAVIS CHARLES QUENTIN , COLEMAN DAVID , SHETTY SURAJ , TRAPATHI VINAY , JOSHI KAMINI
发明人： MICHON FRANCIS , MOORE SAMUEL L , FUSCO PETER C , WOHLSTADTER SAMUEL J , DAVIS CHARLES QUENTIN , COLEMAN DAVID , SHETTY SURAJ , TRAPATHI VINAY , JOSHI KAMINI
IPC分类号： G06Q10/00 , G06Q50/00
CPC分类号： G06Q10/00 , G06F19/18 , G06F19/24 , G06Q50/22 , Y02A90/22 , Y02A90/24 , Y02A90/26
摘要： A system and method for assessing the immunological status of one or more individuals in a patient population is presented. The method includes establishing a database comprising a plurality of records of information each representative of the immune status of an individual in the population, each of said records including (1) current information from one or more assays for the presence of a biochemical, and (2) individual specific information comprising one or more of said individual's medical history, said individual's doctors' observations and historical, demographic, lifestyle, and familial information relating to said individual. The method further includes processing the information in said database to find trends or patterns relating to the. immune status of individuals in said patient population; and using the said trends or patterns as part of a health care related decision making process. In exemplary embodiments of the present invention, processing the information in the database includes generating a list of correlations between variables or fields in the database, and for each correlation in the list generating a set of hypotheses that may explain said correlation. In exemplary embodiments of the present invention, as to each hypothesis in the set, automatically refuting, supporting or stating that there is insufficient data to analyze said hypothesis by further processing of the database; and reporting the correlations, their associated hypotheses and the refutation, support, or determination of insufficient data to refute or support, to a user.
摘要翻译：提出了一种用于评估患者群体中一个或多个个体的免疫状态的系统和方法。该方法包括建立数据库，该数据库包括多个代表个体在个体中的免疫状态的信息记录，每个所述记录包括（1）来自一个或多个生物化学物质存在的测定的当前信息，和 2）个体特定信息，其包括所述个人的病史，所述个人的医生观察以及与所述个人有关的历史，人口，生活方式和家庭信息中的一个或多个。该方法还包括处理所述数据库中的信息以找出与该数据库有关的趋势或模式。个体在所述患者群体中的免疫状态; 并将所述趋势或模式用作与保健相关的决策过程的一部分。在本发明的示例性实施例中，处理数据库中的信息包括生成数据库中的变量或字段之间的相关性的列表，以及生成可以解释所述相关性的一组假设中的每个相关。在本发明的示例性实施例中，关于集合中的每个假设，通过进一步处理数据库自动驳斥，支持或指出没有足够的数据来分析所述假设; 并向用户报告相关性，相关假设以及不足数据的反驳，支持或确定。

6. 发明申请

WO2007002579A2 ASSAY CARTRIDGES AND METHODS FOR POINT OF CARE INSTRUMENTS 审中-公开
标题翻译：测量仪器和点心仪器的方法
公开(公告)号：WO2007002579A2
公开(公告)日：2007-01-04
申请号：PCT/US2006/024790
申请日：2006-06-23
申请人： BIOVERIS CORPORATION , DAVIS, Charles, Quentin , LILJESTRAND, John , LELAND, Jonathan , BLANKFARD, Martin , MILLER, Jonathan, M.
发明人： DAVIS, Charles, Quentin , LILJESTRAND, John , LELAND, Jonathan , BLANKFARD, Martin , MILLER, Jonathan, M.
IPC分类号： A61B5/151 , A61B5/157 , B01L3/00 , G01N33/543 , G01N33/53
CPC分类号： G01N33/582 , A61B5/14546 , A61B5/150022 , A61B5/150213 , A61B5/150221 , A61B5/150229 , A61B5/150251 , A61B5/150358 , A61B5/150389 , A61B5/150503 , A61B5/150755 , A61B5/150786 , A61B5/150793 , A61B5/150862 , A61B5/15087 , A61B5/150893 , A61B5/15107 , A61B5/15117 , A61B5/15142 , A61B5/157 , A61B5/411 , B01L3/502715 , B01L3/502723 , B01L3/502738 , B01L3/502753 , B01L3/502761 , B01L3/502776 , B01L7/00 , B01L9/527 , B01L2200/027 , B01L2200/0636 , B01L2200/0647 , B01L2200/0668 , B01L2200/10 , B01L2300/022 , B01L2300/0627 , B01L2300/0645 , B01L2300/0681 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2300/0874 , B01L2300/1805 , B01L2300/1861 , B01L2300/1877 , B01L2400/0406 , B01L2400/0442 , B01L2400/046 , B01L2400/0481 , B01L2400/0487 , B01L2400/0633 , B01L2400/0677 , B01L2400/0683 , B01L2400/0688 , G01N21/6428 , G01N21/648 , G01N21/8483 , G01N33/5002 , G01N33/5302 , G01N33/54326 , G01N33/54346 , G01N33/54386 , G01N35/0098 , G01N2035/00108
摘要： Devices and methods are provided for performing a test to detect and/or quantify the presence of an analyte of interest within a sample using a portable instrument.
摘要翻译：提供了装置和方法，用于使用便携式仪器进行测试以检测和/或定量样品内感兴趣的分析物的存在。

7. 发明申请

WO2009061514A1 AUTOMATED SYSTEMS AND METHODS FOR OBTAINING, STORING, PROCESSING AND UTILIZING IMMUNOLOGIC AND OTHER INFORMATION OF AN INDIVIDUAL AND POPULATION FOR VARIOUS USES 审中-公开
标题翻译：自动化系统和获取，存储，处理和使用个体和人口的各种用途的免疫和其他信息的方法
公开(公告)号：WO2009061514A1
公开(公告)日：2009-05-14
申请号：PCT/US2008/012658
申请日：2008-11-10
申请人： 32 MOTT STREET ACQUISITION I, LLC, d/b/a , MICHON, Francis , MOORE, Samuel, L. , WOHLSTADTER, Samuel, J. , DAVIS, Charles, Quentin , OTERO, Glen , HALEVA, Aaron, S.
发明人： MICHON, Francis , MOORE, Samuel, L. , WOHLSTADTER, Samuel, J. , DAVIS, Charles, Quentin , OTERO, Glen , HALEVA, Aaron, S.
IPC分类号： G06F17/18 , G06Q50/00
CPC分类号： G01N33/5023 , G06F19/24 , G06F19/28
摘要： A system and method for assessing the immunological status of one or more individuals in a patient population Is presented The method includes establishing a database comprising a plurality of records of information each representative of the immune status of individual in the population, each of said records including (1 ) current information from one or more assays for the presence of a biochemical, and (2) individual specific information compπsing one or more of said individual's medical history, said individual's docto observations and historical, demographic, lifestyle, and familial information relating to said individual The method further includes processing the information in said database to find trends or patterns relating to the immune status of individuals in said pati population, and using the said trends or patterns as part of a health care related decision making process.
摘要翻译：用于评估患者群体中一个或多个个体的免疫状态的系统和方法本方法包括建立数据库，该数据库包括多个代表个体在个体中的免疫状态的信息记录，每个记录包括（1）来自一种或多种用于生物化学物质存在的测定的现有信息，和（2）压制所述个体的病史中的一种或多种的个体特异性信息，所述个体的病历观察和与之相关的历史，人口统计学，生活方式和家族性信息所述个体该方法还包括处理所述数据库中的信息以发现与所述pati群体中的个体的免疫状态相关的趋势或模式，并且将所述趋势或模式用作与保健相关的决策过程的一部分。

8. 发明申请

WO2008045819A3 DETECTION AND IDENTIFICATION OF ORGANISMS VIA ANALYSIS OF NUCLEIC ACID SEQUENCES 审中-公开
标题翻译：通过核酸序列分析检测和鉴定有机体
公开(公告)号：WO2008045819A3
公开(公告)日：2008-11-06
申请号：PCT/US2007080685
申请日：2007-10-08
申请人： BIOVERIS CORP , ASTATKE MEKBIB , DAVIS CHARLES QUENTIN
发明人： ASTATKE MEKBIB , DAVIS CHARLES QUENTIN
IPC分类号： C12Q1/68 , C07H21/02
CPC分类号： C12Q1/683 , C12Q1/6846 , C12Q2565/537 , C12Q2521/301
摘要： The present invention relates to methods, compositions, and kits for identifying one or more organisms in a sample. The invention uses a combination of nucleic acid amplification, detectable labels, and restriction enzyme digestion of the amplified nucleic acid.
摘要翻译：本发明涉及用于鉴定样品中的一种或多种生物体的方法，组合物和试剂盒。本发明使用核酸扩增，可检测标记和扩增核酸的限制酶消化的组合。

9. 发明申请

WO2008045819A2 DETECTION AND IDENTIFICATION OF ORGANISMS VIA ANALYSIS OF NUCLEIC ACID SEQUENCES 审中-公开
标题翻译：核酸序列分析对有机体的检测和鉴定
公开(公告)号：WO2008045819A2
公开(公告)日：2008-04-17
申请号：PCT/US2007/080685
申请日：2007-10-08
申请人： BIOVERIS CORPORATION , ASTATKE, Mekbib , DAVIS, Charles, Quentin
发明人： ASTATKE, Mekbib , DAVIS, Charles, Quentin
IPC分类号： C12Q1/68
CPC分类号： C12Q1/683 , C12Q1/6846 , C12Q2565/537 , C12Q2521/301
摘要： The present invention relates to methods, compositions, and kits for identifying one or more organisms in a sample. The invention uses a combination of nucleic acid amplification, detectable labels, and restriction enzyme digestion of the amplified nucleic acid.
摘要翻译：本发明涉及用于鉴定样品中的一种或多种生物体的方法，组合物和试剂盒。本发明使用核酸扩增，可检测标记和扩增核酸的限制酶消化的组合。

10. 发明申请

WO2005114175A2 DETECTION DEVICE, COMPONENTS OF A DETECTION DEVICE, AND METHODS ASSOCIATED THEREWITH 审中-公开
标题翻译：检测装置，检测装置的部件及其相关方法
公开(公告)号：WO2005114175A2
公开(公告)日：2005-12-01
申请号：PCT/US2005/014105
申请日：2005-04-26
申请人： BIOVERIS CORPORATION , DAVIS, Charles, Quentin , COOK, Richard , MATIKYAN, Rober, Kirkor , KOCHAR, Manish, Swarnaraj , HARLEY, Jason, Charles , MILLER, Jonathan, Matthew , DANIELS, Jeffrey, Arthur
发明人： DAVIS, Charles, Quentin , COOK, Richard , MATIKYAN, Rober, Kirkor , KOCHAR, Manish, Swarnaraj , HARLEY, Jason, Charles , MILLER, Jonathan, Matthew , DANIELS, Jeffrey, Arthur
IPC分类号： G01N33/00
CPC分类号： G01N35/028 , G01N2035/042
摘要： A detection system may include a moveable tray configured to hold a multi-cell container of one or more reagents and/or one or more samples. A driving mechanism may be configured to reciprocate the tray in the first linear direction to agitate contents of the container, and may be configured to conduct electrochemiluminescence or other measurements on samples located in the container. The system may include an apparatus for retaining a container, a device for detecting the presence of a container, an apparatus for training a probe to locate and aspirate one or more reagents and/or one or more samples, a latching mechanism for moving parts in the system, and/or a positive displacement pump. A controller may be configured to control linear reciprocation of the tray to have one of a piecewise constant velocity profile and piecewise constant acceleration profile in which the number of piecewise constants does not exceed 24.
摘要翻译：检测系统可以包括配置成容纳一个或多个试剂和/或一个或多个样品的多细胞容器的可移动托盘。驱动机构可以被配置为使托盘沿第一线性方向往复移动以搅拌容器的内容物，并且可以被配置为对位于容器中的样品进行电化学发光或其它测量。该系统可以包括用于保持容器的装置，用于检测容器的存在的装置，用于训练探针以定位和吸出一个或多个试剂和/或一个或多个样品的装置，用于将部件移动系统和/或容积式泵。控制器可以被配置为控制托盘的线性往复运动以具有分段恒定速度分布和分段恒定加速度分布之一，其中分段常数的数量不超过24。

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