发明专利
ZA200900070B Hydroxylated and methoxylated cyclopenta [D] pyrimidines as AKT protein kinase inhibitors
未知
基本信息:
- 专利标题： Hydroxylated and methoxylated cyclopenta [D] pyrimidines as AKT protein kinase inhibitors
- 申请号：ZA200900070 申请日：2009-01-05
- 公开(公告)号：ZA200900070B 公开(公告)日：2010-03-31
- 发明人： MITCHELL IAN S , BLAKE JAMES F , XU RUI , KALLAN NICHOLAS C , XIAO DENGMING , SPENCER KEITH LEE , BENCSIK JOSEF R , LIANG JUN , SAFINA BRIAN , ZHANG BIRONG , CHABOT CHRISTINE , DO STEVEN , WALLACE ELI M , BANKA ANNA L , SCHLACHTER STEPHEN T
- 申请人： ARRAY BIOPHARMA INC , GENENTECH INC
- 专利权人： ARRAY BIOPHARMA INC,GENENTECH INC
- 当前专利权人： ARRAY BIOPHARMA INC,GENENTECH INC
- 优先权： US81871806 2006-07-06
- 主分类号： A61K
- IPC分类号： A61K20100101 ; A61P20100101 ; C07D20100101
摘要：
The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula I for use in oral dosage forms: Also provided are oral dosage forms comprising these compounds, methods of using the compounds and oral dosage forms of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer. Further provided are intermediate compounds from the synthesis of these compounds.
信息查询:
EspacenetIPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |