基本信息:
- 专利标题： MULTI-LAYERED BIOMIMETIC OSTEOCHONDRAL IMPLANTS
- 申请号：PCT/US2022/036016 申请日：2022-07-01
- 公开(公告)号：WO2023278875A1 公开(公告)日：2023-01-05
- 发明人： FRYMAN, James, Craig , HAWKINS, Michael, E. , SAHNEY, Mira , MYUNG, David
- 申请人： HYALEX ORTHOPAEDICS, INC.
- 申请人地址： 99 Hayden Avenue, Building D, Suite 340
- 专利权人： HYALEX ORTHOPAEDICS, INC.
- 当前专利权人： HYALEX ORTHOPAEDICS, INC.
- 当前专利权人地址： 99 Hayden Avenue, Building D, Suite 340
- 代理机构： LARSEN, Charles, D. et al.
- 优先权： US17/365,135 2021-07-01
- 主分类号： A61F2/30
- IPC分类号： A61F2/30 ; A61L27/36 ; A61F2/2803 ; A61F2/30756 ; A61F2002/2825 ; A61F2002/2853 ; A61F2002/2871 ; A61F2002/2892 ; A61F2002/2896 ; A61F2002/30011 ; A61F2002/30014 ; A61F2002/30024 ; A61F2002/30031 ; A61F2002/30062 ; A61F2002/30075 ; A61F2002/30092 ; A61F2002/30324 ; A61F2002/30448 ; A61F2002/30673 ; A61F2002/30757 ; A61F2002/3092 ; A61F2002/30971 ; A61F2310/00017 ; A61F2310/00023 ; A61F2310/00029 ; A61F2310/00071 ; A61F2310/00089 ; A61F2310/00131 ; A61F2310/00179 ; A61F2310/00293 ; A61F2310/00592
摘要：
Provided herein are biomimetic osteochondral implants (100) that are generally useful for the at least partial resurfacing of damaged cartilage within a joint. The implants are constructed to have a modular, layered structure in which the physical properties (e.g., stiffness and lubricity) or dimensions of each layer can be adjusted (e.g., by using the appropriate material and controlling the thickness thereof) based on the anatomy to be replaced. For example, the material and or thicknesses of the layers can be selected to approximate the physical properties and/or dimensions of cartilage (and, optionally, chondral and subchondral bone).