基本信息:
- 专利标题： USE OF THERMOSTABLE EXOSHELLS FOR LYOPHILIZATION OF LABILE SUBSTRATES
- 申请号：PCT/SG2022/050758 申请日：2022-10-25
- 公开(公告)号：WO2023075684A2 公开(公告)日：2023-05-04
- 发明人： DRUM, Chester Lee , VALLERINTEAVIDE MAVELLI, Girish , SADEGHI, Samira
- 申请人： NATIONAL UNIVERSITY OF SINGAPORE
- 申请人地址： 21 Lower Kent Ridge Road,
- 专利权人： NATIONAL UNIVERSITY OF SINGAPORE
- 当前专利权人： NATIONAL UNIVERSITY OF SINGAPORE
- 当前专利权人地址： 21 Lower Kent Ridge Road,
- 代理机构： DOWSING, Bruce John
- 优先权： SG10202111893Q 2021-10-26
- 主分类号： F26B5/06
- IPC分类号： F26B5/06 ; A61K47/42 ; A61K9/19
摘要：
The present invention relates to a method of preparing improved powder forms of bioactive molecules. More particularly, the present invention provides a method of using engineered thermostable ferritin assemblies with excipient qualities to minimise structural and/or functional loss of labile substrates in lyophilization and storage. The present invention also provides freeze-dried compositions obtained by this method and their use in therapeutics.
IPC结构图谱:
| F | 机械工程；照明；加热；武器；爆破 |
| --F26 | 干燥 |
| ----F26B | 从固体材料或制品中消除液体的干燥 |
| ------F26B5/00 | 不需要使用加热方法干燥固体材料或制品 |
| --------F26B5/04 | .借助在低压下湿气的蒸发或升华，例如在真空中 |
| ----------F26B5/06 | ..需要冷冻过程的 |