基本信息:
- 专利标题： METHODS AND SYSTEMS FOR PROCESSING IN REAL-TIME AND USING GAUSSIAN
- 申请号：PCT/IB2022/059434 申请日：2022-10-03
- 公开(公告)号：WO2023057881A1 公开(公告)日：2023-04-13
- 发明人： BRADAU, Calin , BINKO, Thomas , ALBEANU, Nicolae
- 申请人： DH TECHNOLOGIES DEVELOPMENT PTE. LTD.
- 申请人地址： 33 Marsiling Industrial Estate Road 3
- 专利权人： DH TECHNOLOGIES DEVELOPMENT PTE. LTD.
- 当前专利权人： DH TECHNOLOGIES DEVELOPMENT PTE. LTD.
- 当前专利权人地址： 33 Marsiling Industrial Estate Road 3
- 优先权： US63/252,306 2021-10-05
- 主分类号： H01J49/00
- IPC分类号： H01J49/00 ; H01J49/40 ; H01J49/0036
摘要：
Systems and methods are provided for processing in real-time and using Gaussian fitting digitized signals from ions detection in time-of-flight (TOP) mass spectrometry. Acquisition/analog-to- digital conversion may be applied in the course of Ion detection during time-of-flight (TOP) mass spectrometry, with the acquisition/analog-to-digital conversion including generating, in response to detection of ions, one or more time-of-flight (TOP) based signals, and digitizing, using analog- to-digital conversion, the one or more TOP based signals, to generate corresponding digitized data. The digitized data may then be processed, in real-time and based on use of Gaussian fitting, to generate result data corresponding to the time-of-flight (TOP) mass spectrometry. The Gaussian fitting may comprise applying second (2nd) degree polynomial fit, such as by least squares via QR factorization.