基本信息:
- 专利标题： SPECIALIST SIGNAL PROFILERS FOR BASE CALLING
- 申请号：PCT/US2022/037226 申请日：2022-07-14
- 公开(公告)号：WO2023003758A1 公开(公告)日：2023-01-26
- 发明人： KAGALWALLA, Abde Ali Hunaid , OJARD, Eric Jon , MEHIO, Rami , PARNABY, Gavin Derek , UDPA, Nitin , VIECELI, John S.
- 申请人： ILLUMINA SOFTWARE, INC.
- 申请人地址： 5200 Illumina Way
- 专利权人： ILLUMINA SOFTWARE, INC.
- 当前专利权人： ILLUMINA SOFTWARE, INC.
- 当前专利权人地址： 5200 Illumina Way
- 代理机构： FUNK, Christopher C. et al.
- 优先权： US17/839,353 2022-06-13
- 主分类号： G16B40/10
- IPC分类号： G16B40/10 ; G16B40/20 ; G16B30/00 ; C12Q1/6869
摘要：
We disclose a system. The system comprises a memory and a runtime logic. The memory stores a plurality of specialist signal profilers. Each specialist signal profiler in the plurality of specialist signal profilers is trained to maximize signal-to-noise ratio of sequenced signals in a particular signal profile detected for analytes in a particular analyte class and characterized in a particular training data set. The runtime logic, having access to the memory, is configured to execute a base calling operation by applying respective specialist signal profilers in the plurality of specialist signal profilers to sequenced signals in respective signal profiles detected for analytes in respective analyte classes during the base calling operation.