发明申请
WO2022271476A1 FORMULATIONS OF ACTIVE PHARMACEUTICAL INGREDIENTS (APIS) FOR LOCAL DELIVERY VIA ACTIVE MICROBOT
审中-公开
基本信息:
- 专利标题： FORMULATIONS OF ACTIVE PHARMACEUTICAL INGREDIENTS (APIS) FOR LOCAL DELIVERY VIA ACTIVE MICROBOT
- 申请号：PCT/US2022/033256 申请日：2022-06-13
- 公开(公告)号：WO2022271476A1 公开(公告)日：2022-12-29
- 发明人： KISELYOV, Alex
- 申请人： BIONAUT LABS LTD. , KISELYOV, Alex
- 申请人地址： 1 Arie Shenkar Street; 4203 Shorepointe Way
- 专利权人： BIONAUT LABS LTD.,KISELYOV, Alex
- 当前专利权人： BIONAUT LABS LTD.,KISELYOV, Alex
- 当前专利权人地址： 1 Arie Shenkar Street; 4203 Shorepointe Way
- 代理机构： COHEN, Mark et al.
- 优先权： US63/213,945 2021-06-23
- 主分类号： A61J3/00
- IPC分类号： A61J3/00 ; B65B43/42 ; A61J3/07 ; A61J7/00 ; A61J3/10 ; A61K9/2072 ; A61K9/2095 ; A61M2025/0042 ; A61M31/002 ; A61M37/00
摘要：
Provided herein are pharmaceutical formulations, methods of manufacturing thereof, and methods of treatment. The pharmaceutical formulations are adapted to serve as a payload on or in a microbot, and comprise a tablet of a therapeutically effective dose of a pharmaceutical agent and have dimensions such that the tablet may fit on or in the microbot. The pharmaceutical formulation may be formed into, e.g., a cylinder or spheroid of 1mm dimension, and the pharmaceutical agent may be a small molecule drug, a peptide, a peptoid, a biologic drug, cells, or any combination thereof. Thus, the pharmaceutical formulation of the present description offers delivery of targeted therapy at a locus in a subject, e.g., a tumor.