基本信息:
- 专利标题： ASSESSING PACKED CELL VOLUME FOR CELL CULTURES
- 申请号：PCT/US2022/032308 申请日：2022-06-06
- 公开(公告)号：WO2022260981A1 公开(公告)日：2022-12-15
- 发明人： CONNER, Jeremy, S. , WHETSTONE, Sarah , KUMAR, Ketan
- 申请人： AMGEN INC.
- 申请人地址： One Amgen Center Drive
- 专利权人： AMGEN INC.
- 当前专利权人： AMGEN INC.
- 当前专利权人地址： One Amgen Center Drive
- 代理机构： BATEMAN, Andrew, W.
- 优先权： US63/208,824 2021-06-09
- 主分类号： C12M1/36
- IPC分类号： C12M1/36 ; C12M1/34
摘要：
A method of cell culture assessment (e.g., prior to a drug substance harvesting process) includes obtaining a plurality of parameters associated with a cell culture, and inferring or predicting a value or classification indicative of packed cell volume. Inferring or predicting the packed cell volume includes applying the plurality of parameters as inputs to a non-linear machine learning model. The method also includes generating an output indicative of the inferred or predicted value or classification.
IPC结构图谱:
| C | 化学；冶金 |
| --C12 | 生物化学；啤酒；烈性酒；果汁酒；醋；微生物学；酶学；突变或遗传工程 |
| ----C12M | 酶学或微生物学装置 |
| ------C12M1/00 | 酶学或微生物学装置 |
| --------C12M1/36 | .包括条件或时间反应控制，如自动控制的发酵器 |