基本信息:
- 专利标题： EXTENDED RELEASE DRUG DELIVERY SYSTEM FOR OCULAR DRUGS AND METHODS OF USE
- 申请号：PCT/US2022/031777 申请日：2022-06-01
- 公开(公告)号：WO2022256412A2 公开(公告)日：2022-12-08
- 发明人： GARCIA, Andres , LIU, Xunpei
- 申请人： EYEDEA BIO, LLC
- 申请人地址： 59501 Cary
- 专利权人： EYEDEA BIO, LLC
- 当前专利权人： EYEDEA BIO, LLC
- 当前专利权人地址： 59501 Cary
- 代理机构： SHOOP, Richard D. et al.
- 优先权： US63/195,697 2021-06-01
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K47/12 ; A61K47/14 ; A61K9/00 ; A61P27/02 ; A61K47/69
摘要：
Described herein are therapeutic compositions and methods of use, for the delivery of various drug substances, in and around the eye, comprising: a drug substance, noncovalently interacting with one or more complexation agent particulates to form drug substance-complex particulates, admixed within a hydrophobic dispersal medium, that collectively forms a stable multiphasic colloidal suspension, that serves as an extended release drug delivery system for ocular drug delivery. Formulation of the drug substance in the multiphasic colloidal suspension can be administered in and around the eye to produce sustained release of therapeutic levels of drug substance within ocular tissues for one or more months without requiring retreatment.
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K38/00 | 含肽的医药配制品 |