基本信息:
- 专利标题： CO-EXPRESSION OF CONSTRUCTS AND IMMUNOINHIBITORY COMPOUNDS
- 申请号：PCT/EP2022/062688 申请日：2022-05-10
- 公开(公告)号：WO2022238432A2 公开(公告)日：2022-11-17
- 发明人： FREDRIKSEN, Agnete Brunsvik , BERSAAS, Audun Trygge Haugen , GRANUM, Stine , MYRSET, Heidi
- 申请人： NYKODE THERAPEUTICS ASA
- 申请人地址： Gaustadalléen 21
- 专利权人： NYKODE THERAPEUTICS ASA
- 当前专利权人： NYKODE THERAPEUTICS ASA
- 当前专利权人地址： Gaustadalléen 21
- 代理机构： HØIBERG P/S
- 优先权： NO20220133 2022-01-26
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K39/35 ; A61P37/06 ; A61P37/08 ; C07K14/00 ; A61K2039/55522 ; A61K2039/55527 ; A61K2039/55533 ; A61K2039/6031 ; A61K2039/6056 ; A61K2039/627 ; A61K2039/70 ; A61K39/0008 ; C07K2319/02 ; C07K2319/30 ; C07K2319/32 ; C07K2319/40 ; C07K2319/74 ; C12N15/85
摘要：
The present invention relates to vectors, such as DNA plasmids, comprising multiple nucleic acid sequences engineered to be co-expressed as separate molecules. Such separate molecules include a first polypeptide, wherein the first polypeptide comprises a targeting unit that targets antigen-presenting cells, a multimerization unit, such as dimerization unit, and an antigenic unit comprising one or more T cell epitopes of a self-antigen, an allergen, an alloantigen or a xenoantigen, and one or more immunoinhibitory compounds
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K39/00 | 含有抗原或抗体的医药配制品 |