基本信息:
- 专利标题： FORMULATION AND METHOD FOR TREATMENT OF URINARY SYSTEM DISORDERS
- 申请号：PCT/US2021/026285 申请日：2021-04-07
- 公开(公告)号：WO2022216287A1 公开(公告)日：2022-10-13
- 发明人： KINSELLA JR., Christopher R. , ALI, Saniya , NOLAN, Clay Justin , BARTLETT II, Rush Lloyd
- 申请人： WATERSHED MEDICAL INC
- 申请人地址： 9841 NE 15th Street
- 专利权人： WATERSHED MEDICAL INC
- 当前专利权人： WATERSHED MEDICAL INC
- 当前专利权人地址： 9841 NE 15th Street
- 代理机构： REED, Dianne E. et al.
- 主分类号： A61K9/16
- IPC分类号： A61K9/16 ; A61K31/635 ; A61K33/38 ; A61P13/10
摘要：
The invention provides a formulation and method for the treatment of urinary system disorders, wherein the formulation comprises a controlled release drug delivery system for intravesicular administration to a patient. Controlled release microparticles in the formulation are comprised of a pharmacologically active agent and a controlled release carrier, where the microparticles are buoyant in urine. Microparticle buoyancy in urine ensures that the formulation continues to release the active agent into a patient's bladder throughout the duration of an extended drug delivery time period. Methods of treating urinary system disorders by intravesicular administration of the microparticle formulation to a subject are also provided, and include methods of treating urinary system infections, bladder cancer, incontinence, and other urinary system disorders.
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K9/00 | 以特殊物理形状为特征的医药配制品 |
| --------A61K9/10 | .分散液；乳剂 |
| ----------A61K9/16 | ..块状；粒状；微珠状 |