发明申请
WO2022212643A2 SYSTEMS AND COMPOSITIONS FOR DETECTING A BIOLOGICAL SAMPLE AND METHODS THEREOF
审中-公开
基本信息:
- 专利标题： SYSTEMS AND COMPOSITIONS FOR DETECTING A BIOLOGICAL SAMPLE AND METHODS THEREOF
- 申请号：PCT/US2022/022742 申请日：2022-03-31
- 公开(公告)号：WO2022212643A2 公开(公告)日：2022-10-06
- 发明人： TAFAS, Triantafyllos, P. , KEILICH, Spencer, Ryan
- 申请人： QCDX LLC
- 申请人地址： 400 Farmington Avenue
- 专利权人： QCDX LLC
- 当前专利权人： QCDX LLC
- 当前专利权人地址： 400 Farmington Avenue
- 代理机构： LEE, Sungsoo
- 优先权： US63/169,566 2021-04-01
- 主分类号： G01N1/00
- IPC分类号： G01N1/00 ; G01N21/00 ; G01N33/48 ; G01N33/483 ; G01N1/30 ; C12Q1/68 ; G01N33/533
摘要：
The present invention provides methods and systems for analyzing a biological sample. The methods of the present invention can utilize a labeling moiety and a cleavage moiety. The labeling moiety can comprise a binding moiety that is coupled to a detectable tag via a polynucleotide linker. The cleavage moiety can form a complex with the polynucleotide linker. In some cases, after formation of the complex, the cleavage moiety can effect cleavage of the polynucleotide linker, to release the detectable tag from the binding moiety. The release of the detectable tag can allow one or more additional imaging of the biological sample with a different labeling moiety that comprises a different binding moiety but the same labeling moiety.
IPC结构图谱:
| G | 物理 |
| --G01 | 测量；测试 |
| ----G01N | 借助于测定材料的化学或物理性质来测试或分析材料 |
| ------G01N1/00 | 取样；制备测试用的样品 |