发明申请
WO2022166978A1 GENETICALLY GENGINEERED BACTERIUM FOR HANGOVER AND LIVER DISEASE PREVENTION AND/OR TREATMENT
审中-公开
基本信息:
- 专利标题： GENETICALLY GENGINEERED BACTERIUM FOR HANGOVER AND LIVER DISEASE PREVENTION AND/OR TREATMENT
- 申请号：PCT/CN2022/075470 申请日：2022-02-08
- 公开(公告)号：WO2022166978A1 公开(公告)日：2022-08-11
- 发明人： XIANG, Bin , YIN, Shengming , WANG, Yanning
- 申请人： COMMBIO THERAPEUTICS CO., LTD.
- 申请人地址： Room 504, No. 781 Cailun Road, Shanghai Free Trade Pilot Zone, Pudong New Area
- 专利权人： COMMBIO THERAPEUTICS CO., LTD.
- 当前专利权人： COMMBIO THERAPEUTICS CO., LTD.
- 当前专利权人地址： Room 504, No. 781 Cailun Road, Shanghai Free Trade Pilot Zone, Pudong New Area
- 代理机构： JUN HE LAW OFFICES
- 优先权： CNPCT/CN2021/076102 2021-02-08
- 主分类号： C12N1/21
- IPC分类号： C12N1/21 ; C12N15/70 ; C12N15/53 ; A23C9/13 ; A61K35/741 ; A61K38/44 ; A61P25/32 ; A61P1/16 ; C12R1/19
摘要：
Provided are a genetically engineered probiotic intestinal bacterium, comprising an exogenous expression cassette comprising a nucleotide sequence that encodes acetaldehyde dehydrogenase, wherein the probiotic intestinal bacterium is Escherichia coli strain Nissle 1917 (EcN), and uses thereof.