发明申请
WO2022150608A1 COMPOSITIONS COMPRISING A VARIANT CRISPR NUCLEASE POLYPEPTIDE AND USES THEREOF
审中-公开
基本信息:
- 专利标题： COMPOSITIONS COMPRISING A VARIANT CRISPR NUCLEASE POLYPEPTIDE AND USES THEREOF
- 申请号：PCT/US2022/011647 申请日：2022-01-07
- 公开(公告)号：WO2022150608A1 公开(公告)日：2022-07-14
- 发明人： CHONG, Shaorong , HILBERT, Brendan Jay , GUZOV, Victor, Mikhailovich , JONES, Austin McCarty
- 申请人： ARBOR BIOTECHNOLOGIES, INC.
- 申请人地址： 20 Acorn Park Drive, Tower 500
- 专利权人： ARBOR BIOTECHNOLOGIES, INC.
- 当前专利权人： ARBOR BIOTECHNOLOGIES, INC.
- 当前专利权人地址： 20 Acorn Park Drive, Tower 500
- 代理机构： BEHROOZ, Alireza et al.
- 优先权： US63/135,090 2021-01-08
- 主分类号： C12N15/10
- IPC分类号： C12N15/10 ; C12N15/90 ; C12N9/22 ; C40B40/06 ; C40B50/06
摘要：
The present invention relates to variant CRISPR nuclease polypeptides, methods of preparing the variant CRISPR nuclease polypeptides, processes for characterizing the variant CRISPR nuclease polypeptides, compositions and cells comprising the variant CRISPR nuclease polypeptides, and methods of using the variant CRISPR nuclease polypeptides. The invention further relates to complexes comprising a variant CRISPR nuclease polypeptide, methods of producing the complexes, processes for characterizing the complexes, cells comprising the complexes, and methods of using the complexes.