基本信息:
- 专利标题： METHODS OF TREATING LYMPHOPENIA
- 申请号：PCT/US2021/057985 申请日：2021-11-04
- 公开(公告)号：WO2022098821A1 公开(公告)日：2022-05-12
- 发明人： SEEHRA, Jasbir, S. , LACHEY, Jennifer , ROVALDI, Christopher, R. , ORDONEZ, Claudia
- 申请人： KEROS THERAPEUTICS, INC.
- 申请人地址： 99 Hayden Avenue
- 专利权人： KEROS THERAPEUTICS, INC.
- 当前专利权人： KEROS THERAPEUTICS, INC.
- 当前专利权人地址： 99 Hayden Avenue
- 代理机构： BELLIVEAU, Michael, J.
- 优先权： US63/109,864 2020-11-04
- 主分类号： C07K14/51
- IPC分类号： C07K14/51 ; C07K16/22 ; C07K16/26 ; C07K16/28
摘要：
The invention features methods of treating or preventing lymphopenia in a subject treated with a BMP inhibitor or a hepcidin inhibitor, such as an ALK2 inhibitor, by co-administering an iron supplement with the inhibitor, and methods of treating a subject who has or is at risk of developing a disease or condition that can be treated with a BMP inhibitor or a hepcidin inhibitor, such as an ALK2 inhibitor, by administering to the subject a BMP inhibitor or a hepcidin inhibitor and an iron supplement.
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07K | 肽 |
| ------C07K14/00 | 具有多于20个氨基酸的肽；促胃液素；生长激素释放抑制因子；促黑激素；其衍生物 |
| --------C07K14/415 | .来自植物 |
| ----------C07K14/44 | ..来自原生动物门 |
| ------------C07K14/51 | ...骨形态形成因子；骨生成素；成骨因子；骨诱导因子 |