基本信息:
- 专利标题： BIOMARKER METHODS AND USES
- 申请号：PCT/EP2021/075629 申请日：2021-09-17
- 公开(公告)号：WO2022058505A1 公开(公告)日：2022-03-24
- 发明人： ZETTL, Markus , KASTRESANA, Aizea Morales , WURZENBERGER, Cornelia , PEPER-GABRIEL, Janet , RICHTER, Marleen , ANDERSEN, Nicole , BEL AIBA, Rachida , ALLERSDORFER, Andrea , NODERER, Verena
- 申请人： PIERIS PHARMACEUTICALS GMBH
- 申请人地址： Zeppelinstrasse 3
- 专利权人： PIERIS PHARMACEUTICALS GMBH
- 当前专利权人： PIERIS PHARMACEUTICALS GMBH
- 当前专利权人地址： Zeppelinstrasse 3
- 代理机构： SCHIWECK, Wolfram et al.
- 优先权： US63/080,361 2020-09-18
- 主分类号： A61P35/00
- IPC分类号： A61P35/00 ; C07K14/00 ; C07K16/32 ; A61K39/00 ; C07K14/705 ; C07K16/28 ; G01N33/574
摘要：
The disclosure provides methods for predicting a positive clinical outcome for a cancer patient upon treatment with a 4-1BB agonistic agent, for assessing activity of such 4-1BB agonistic agent in a subject, preferably a cancer patient, and for selecting a dose of a 4-1BB agonistic agent for treating a disease, such as cancer. The disclosure also provides methods of treating cancer as well as uses of biomarkers and uses of kits for their detection.
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61P | 化合物或药物制剂的治疗活性 |
| ------A61P35/00 | 抗肿瘤药 |