基本信息:
- 专利标题： RECOMBINANT ALGAE HAVING HIGH LIPID PRODUCTIVITY
- 申请号：PCT/US2021/049708 申请日：2021-09-09
- 公开(公告)号：WO2022056155A1 公开(公告)日：2022-03-17
- 发明人： IMAM, Saheed , MOELLERING, Eric R. , PEACH, Luke , LAMBERT, William F. , WEIR, Jessica
- 申请人： SYNTHETIC GENOMICS, INC.
- 申请人地址： 11149 North Torrey Pines Road
- 专利权人： SYNTHETIC GENOMICS, INC.
- 当前专利权人： SYNTHETIC GENOMICS, INC.
- 当前专利权人地址： 11149 North Torrey Pines Road
- 代理机构： HAILE, Lisa A. et al.
- 优先权： US63/077,474 2020-09-11
- 主分类号： C07H21/04
- IPC分类号： C07H21/04 ; C07K14/405 ; C12N1/12 ; C12N1/13 ; C12N1/36
摘要：
The invention provides recombinant algal organisms that have a genetic modification to a gene or nucleic acid sequence encoding an RNA binding domain. In some embodiments the genetic modification can be a functional deletion or attenuation of the gene. The genetic modification results in a mutant organism with increased lipid productivity and/or higher biomass productivity. The lipid products of these mutants can be utilized as biofuels or to manufacture other specialty products. The recombinant mutants can also, optionally, have a genetic modification to a gene encoding an SGI1 polypeptide. Methods of making and using the recombinant algal mutants and methods of producing lipids are also disclosed.
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07H | 糖类；及其衍生物；核苷；核苷酸；核酸 |
| ------C07H21/00 | 含有两个或多个单核苷酸单元的化合物，具有以核苷基的糖化物基团连接的单独的磷酸酯基或多磷酸酯基，例如核酸 |
| --------C07H21/04 | .以脱氧核糖基作为糖化物基团 |