发明申请
WO2022026921A8 IDENTIFICATION AND USE OF T CELL EPITOPES IN DESIGNING DIAGNOSTIC AND THERAPEUTIC APPROACHES FOR COVID-19
审中-公开
基本信息:
- 专利标题： IDENTIFICATION AND USE OF T CELL EPITOPES IN DESIGNING DIAGNOSTIC AND THERAPEUTIC APPROACHES FOR COVID-19
- 申请号：PCT/US2021/044063 申请日：2021-07-30
- 公开(公告)号：WO2022026921A8 公开(公告)日：2022-02-03
- 发明人： PREGIBON, Daniel , FRANCIS, Joshua , LEISTRITZ-EDWARDS, Del , DUNN, William , ESTRADA, Violeta Rayon , LIU, Gang , KISIELOW, Jan , OBERMAIR, Franz-Josef
- 申请人： REPERTOIRE IMMUNE MEDICINES, INC. , REPERTOIRE IMMUNE MEDICINES (SWITZERLAND) LTD.
- 申请人地址： 26 Landsdowne Street, Suite 300; Wagistrasse 27
- 专利权人： REPERTOIRE IMMUNE MEDICINES, INC.,REPERTOIRE IMMUNE MEDICINES (SWITZERLAND) LTD.
- 当前专利权人： REPERTOIRE IMMUNE MEDICINES, INC.,REPERTOIRE IMMUNE MEDICINES (SWITZERLAND) LTD.
- 当前专利权人地址： 26 Landsdowne Street, Suite 300; Wagistrasse 27
- 代理机构： LILY WEN XU
- 优先权： US63/059,144 2020-07-30
- 主分类号： A61K35/17
- IPC分类号： A61K35/17 ; A61K38/00 ; A61K39/12 ; C07K14/005 ; C12N2770/20022 ; C12N2770/20034
摘要：
Approaches for identifying T cell epitopes from SARS-CoV-2 are provided, along with the use of such T cell epitopes diagnostically and therapeutically. Compositions including T cell epitope vaccines and T cell epitope-display reagents are provided. Methods for identifying SARS-CoV-2 T cell epitopes, methods of identifying reactive T cells and methods of using epitopes and T cells for diagnostic purposes, such as identifying particular patient subpopulations are provided. Treatment methods, including administration of T cell epitope vaccines prophylactically and administration of activated T cells therapeutically are also provided.
公开/授权文献:
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K35/00 | 含有其有不明结构的原材料或其反应产物的医用配制品 |
| --------A61K35/02 | .来源于非生命物质的 |
| ----------A61K35/14 | ..血液 |
| ------------A61K35/17 | ...淋巴细胞；B细胞；T细胞；自然杀伤细胞；干扰素激活或细胞因子激活的淋巴细胞 |