基本信息:
- 专利标题： 成熟脂肪細胞含有組成物の製造方法
- 专利标题（英）：METHOD FOR PRODUCING MATURE ADIPOCYTE-CONTAINING COMPOSITION
- 申请号：PCT/JP2021/001133 申请日：2021-01-14
- 公开(公告)号：WO2022014071A1 公开(公告)日：2022-01-20
- 发明人： 矢永 博子 , 矢永 茄津
- 申请人： 医療法人Ｙａｎａｇａ ＣＬｉｎｉｃ
- 申请人地址： 〒8100001 福岡県福岡市中央区天神一丁目２番１２号 Fukuoka
- 专利权人： 医療法人Ｙａｎａｇａ ＣＬｉｎｉｃ
- 当前专利权人： 医療法人Ｙａｎａｇａ ＣＬｉｎｉｃ
- 当前专利权人地址： 〒8100001 福岡県福岡市中央区天神一丁目２番１２号 Fukuoka
- 代理机构： 廣瀬 隆行
- 优先权： JP2020-122512 2020-07-17
- 主分类号： C12N5/077
- IPC分类号： C12N5/077 ; A61F2/06 ; A61F2/12 ; A61K35/35 ; A61P9/00 ; C12N5/06
[Problem] To provide a mature adipocyte-containing composition that has excellent revascularization ability and is less likely to cause inflammation. [Solution] This method for producing a mature adipocyte-containing composition comprises: a cleavage-filtration step for cleaving and filtering fatty tissue that is not treated with an enzyme and obtaining a minimal fat; a minimal fat culture step for culturing the minimal fat, after the cleavage-filtration step, by means of a culture medium, and obtaining mature adipocytes; and a mature adipocyte-containing composition obtaining step for obtaining a mature adipocyte-containing composition including the mature adipocytes and a conditioned medium obtained from the minimal fat culture step, wherein the culture medium contains an autoserum or contains FBS, hydrocortisone, and FGF-2.