基本信息:
- 专利标题： SELF-ASSEMBLING PEPTIDE GEL FORMULATION AND METHODS OF USE
- 申请号：PCT/US2021/013249 申请日：2021-01-13
- 公开(公告)号：WO2021146291A1 公开(公告)日：2021-07-22
- 发明人： NORCHI, Terrence , SHAH, Chirag , ELLIS-BEHNKE, Rutledge
- 申请人： ARCH BIOSURGERY, INC.
- 申请人地址： 235 Walnut Street
- 专利权人： ARCH BIOSURGERY, INC.
- 当前专利权人： ARCH BIOSURGERY, INC.
- 当前专利权人地址： 235 Walnut Street
- 代理机构： PABST, Patrea L. et al.
- 优先权： US62/960,550 2020-01-13
- 主分类号： A61K38/10
- IPC分类号： A61K38/10 ; A61K45/06 ; A61P7/04 ; A61P19/04 ; A61L2400/04 ; A61L2400/06 ; A61L27/22 ; A61L27/52 ; A61L27/58 ; A61P43/00 ; C07K2319/735 ; C07K7/08
摘要：
Compositions containing self-assembling peptides and/or self-assembling peptidomimetics ("self-assembling peptides") can be used to create a long-lasting "lift" or means of elevating tissue to be resected, dissected, manipulated or repaired, as a bulking agent, or as a tissue forming matrix by injection of a solution that forms a solid gel in situ, which is stable for a prolonged period of time from days to a month, is hemostatic, and may prevent adhesions. These self-assembling peptides and methods of use thereof enable better separation of tissues and visualization of margins, more durable and robust lifts, less need for frequent injections that carry risk of undesired perforation, and simultaneous management of adverse effects, such as bleeding, leaking, inflammation and iatrogenic injury during endoscopic, laparoscopic or other minimally invasive, or open surgical procedures in and/or on the body.
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K38/00 | 含肽的医药配制品 |
| --------A61K38/04 | .在完全确定的序列中最多有20个氨基酸的肽；其衍生物 |
| ----------A61K38/10 | ..含有12～20个氨基酸的肽 |