基本信息:
- 专利标题： AUTOMATED PRODUCTION OF VIRAL VECTORS
- 申请号：PCT/US2019/067354 申请日：2019-12-19
- 公开(公告)号：WO2020132177A1 公开(公告)日：2020-06-25
- 发明人： HEWITT, Matthew , SHIN, Young , GU, Bingnan , GUENTHER, Caitlin M. , SETH, Anandita
- 申请人： LONZA WALKERSVILLE, INC.
- 申请人地址： 8830 Biggs Ford Road Walkersville, Maryland 21793 US
- 专利权人： LONZA WALKERSVILLE, INC.
- 当前专利权人： LONZA WALKERSVILLE, INC.
- 当前专利权人地址： 8830 Biggs Ford Road Walkersville, Maryland 21793 US
- 代理机构： MILLS, Jeffrey K.
- 优先权： US62/783,589 20181221; US62/866,092 20190625; US62/890,904 20190823; US62/949,848 20191218
- 主分类号： C12N15/85
- IPC分类号： C12N15/85 ; C12N15/86 ; C12N5/10 ; C12N7/00
摘要：
The present disclosure provides an automated method of producing viral vectors, utilizing engineered viral vector-producing cell lines within a fully-enclosed cell engineering system. Exemplary viral vectors that can be produced include lentivirus vectors, adeno-associated virus vectors, baculovirus vectors and retrovirus vectors.