发明申请
WO2020069421A3 ADJOINT TRANSPORT FOR DOSE IN TREATMENT TRAJECTORY OPTIMIZATION AND BEAM ANGLE OPTIMIZATION FOR EXTERNAL BEAM RADIATION THERAPY
审中-公开
基本信息:
- 专利标题： ADJOINT TRANSPORT FOR DOSE IN TREATMENT TRAJECTORY OPTIMIZATION AND BEAM ANGLE OPTIMIZATION FOR EXTERNAL BEAM RADIATION THERAPY
- 申请号：PCT/US2019/053623 申请日：2019-09-27
- 公开(公告)号：WO2020069421A3 公开(公告)日：2020-04-02
- 发明人： OLLILA, Santtu , WAREING, Todd Arlin , MCGHEE, John Morton , BARNETT, JR., Douglas Allen , MASLOWSKI, Alexander Enrique
- 申请人： VARIAN MEDICAL SYSTEMS INTERNATIONAL AG , VARIAN MEDICAL SYSTEMS, INC.
- 申请人地址： Hinterbergstrasse 14 CH-6312 Steinhausen CH
- 专利权人： VARIAN MEDICAL SYSTEMS INTERNATIONAL AG,VARIAN MEDICAL SYSTEMS, INC.
- 当前专利权人： VARIAN MEDICAL SYSTEMS INTERNATIONAL AG,VARIAN MEDICAL SYSTEMS, INC.
- 当前专利权人地址： Hinterbergstrasse 14 CH-6312 Steinhausen CH
- 代理机构： LIU, Rong et al.
- 优先权： US62/738,741 20180928
- 主分类号： A61N5/10
- IPC分类号： A61N5/10
摘要：
A method of trajectory optimization for radiotherapy treatment includes providing a patient model having one or more regions of interest (ROIs), defining a delivery coordinate space (DCS), for each ROI, solving an adjoint transport to obtain an adjoint solution field from the ROI, for each vertex in the DCS, evaluating an adjoint photon fluence by performing ray tracing of the adjoint solution field, evaluating a dose of the ROI using the adjoint photon fluence, for each vertex in the DCS, evaluating a respective beam's eye view (BEV) score of each pixel of a BEV plane using the doses of the one or more ROIs, determining one or more BEV regions in the BEV plane based on the BEV scores, determining a BEV region connectivity manifold based on the BEV regions, and determining one or more optimal treatment trajectories based on the BEV region connectivity manifold.
公开/授权文献:
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61N | 电疗；磁疗；放射疗；超声波疗 |
| ------A61N5/00 | 放射疗 |
| --------A61N5/10 | .X射线治疗法，γ射线治疗法；粒子照射疗法 |