基本信息:
- 专利标题： HETEROCYCLIC COMPOUND AND USE THEREOF
- 申请号：PCT/JP2019/014901 申请日：2019-03-27
- 公开(公告)号：WO2019189945A1 公开(公告)日：2019-10-03
- 发明人： OGURO, Yuya , MATSUMOTO, Shigemitsu , WAKABAYASHI, Takeshi , TOKUNAGA, Norihito , KAMEI, Taku , ITO, Mitsuhiro , MIKAMI, Satoshi , SETO, Masaki , MORIMOTO, Shinji , NAKAMURA, Shinji , TAKASHIMA, Sachie , MURAKAMI, Masataka , DAINI, Masaki , KAMATA, Makoto , NAKAMURA, Minoru , WADA, Yasufumi , KAKEI, Hiroyuki , TAKAMI, Kazuaki , TAWARAISHI, Taisuke , AIDA, Jumpei , HIWANAGA, Kouichi , YAMAMOTO, Satoshi
- 申请人： TAKEDA PHARMACEUTICAL COMPANY LIMITED
- 申请人地址： 1-1, Doshomachi 4-chome, Chuo-ku, Osaka-shi, Osaka 5410045 JP
- 专利权人： TAKEDA PHARMACEUTICAL COMPANY LIMITED
- 当前专利权人： TAKEDA PHARMACEUTICAL COMPANY LIMITED
- 当前专利权人地址： 1-1, Doshomachi 4-chome, Chuo-ku, Osaka-shi, Osaka 5410045 JP
- 代理机构： TAKASHIMA, Hajime
- 优先权： JP2018-062939 20180328
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07D487/04 ; A61P25/00 ; A61K31/437 ; A61K31/4162
摘要：
The present invention provides a heterocyclic compound having an antagonistic action on an NMDA receptor containing the NR2B subunit, and expected to be useful as an agent for the prophylaxis or treatment of major depression, bipolar disorder, migraine, pain, behavioral and psychological symptoms of dementia and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as described in the description, or a salt thereof.
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D471/00 | 在稠环系中含有氮原子作为仅有的杂环原子、其中至少1个环是含有1个氮原子的六元环的杂环化合物，C07D451/00至C07D463/00不包括的 |
| --------C07D471/02 | .在稠环系中含两个杂环 |
| ----------C07D471/04 | ..邻位稠环系 |