基本信息:
- 专利标题： Pan-Tropic Entry Inhibitors
- 申请号：PCT/US2019/023022 申请日：2019-03-19
- 公开(公告)号：WO2019183133A1 公开(公告)日：2019-09-26
- 发明人： LIOTTA, Dennis C. , JECS, Edgars , ALTAS TAHIROVIC, Yesim , WILSON, Lawrence , PELLY, Stephen Christopher
- 申请人： EMORY UNIVERSITY
- 申请人地址： Office of Technology Transfer 1599 Clifton Road NE, 4th Floor Atlanta, Georgia 30322 US
- 专利权人： EMORY UNIVERSITY
- 当前专利权人： EMORY UNIVERSITY
- 当前专利权人地址： Office of Technology Transfer 1599 Clifton Road NE, 4th Floor Atlanta, Georgia 30322 US
- 代理机构： MASON, James C. et al.
- 优先权： US62/644,982 20180319
- 主分类号： A61K31/395
- IPC分类号： A61K31/395 ; A61K31/495 ; A61K31/496 ; C07D241/00 ; C07D241/36 ; C07D241/38
摘要：
This disclsore relates to compounds according to Formula (I), salts, prodrugs and pharmaceutical formulation comprising the compound are provided herein for the treatment of CXCR4 and CCR5 related conditions. The conditions may include viral infections, abnormal cellular proliferation, retinal degeneration and inflammatory diseases, or the compounds may be used as immunostimulants or immunosuppressants. Furthermore, the compounds may be used in combination with another active ingredient selected from an antiviral agent or chemotherapeutic agent.
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K31/00 | 含有机有效成分的医药配制品 |
| --------A61K31/33 | .杂环化合物 |
| ----------A61K31/395 | ..有氮作为环杂原子的，例如胍乙啶、利福霉素 |