基本信息:
- 专利标题： METHOD FOR IDENTIFYING GENES ASSOCIATED WITH A PARTICULAR PHENOTYPE
- 申请号：PCT/GB2019/050077 申请日：2019-01-11
- 公开(公告)号：WO2019138244A1 公开(公告)日：2019-07-18
- 发明人： WULFF, Brande Bruce Hertel , ARORA, Sanu , STEUERNAGEL, Burkhard , GAURAV, Kumar
- 申请人： JOHN INNES CENTRE
- 申请人地址： Norwich Research Park Colney Norwich Norfolk NR4 7UH GB
- 专利权人： JOHN INNES CENTRE
- 当前专利权人： JOHN INNES CENTRE
- 当前专利权人地址： Norwich Research Park Colney Norwich Norfolk NR4 7UH GB
- 代理机构： REDDIE & GROSE LLP
- 优先权： GB1800558.7 20180112
- 主分类号： G16B20/20
- IPC分类号： G16B20/20 ; G16B20/40 ; G16B20/50
摘要：
The invention is directed to a method for identifying one or more genes associated with a selected phenotype in an organism. The method includes the steps of screening a database for genetic samples or nucleic acids associated with a selected phenotype, producing enriched sample sequences, identifying sub-sequences of a fixed length k ( k - mers) associated with the selected phenotype within the enriched sample sequences, and mapping the identified k -mers. The method may be used for example to identify genes encoding plant resistance proteins, such as nucleotide-binding and leucine-rich repeat (NLR) proteins.
IPC结构图谱:
| G | 物理 |
| --G16 | 特别适用于特定应用领域的信息通信技术 |
| ----G16B | 生物信息学，例如特别适用于计算分子生物学中的遗传或蛋白质相关数据处理的信息与通信技术 |
| ------G16B20/00 | 特别适用于功能性基因组学或蛋白质组学的，例如基因型-表型关联的ICT |
| --------G16B20/20 | .等位基因或变异检测，例如单核酸多态性 |