基本信息:
- 专利标题: DEEP ULTRAVIOLET-EXCITABLE WATER-SOLVATED POLYMERIC DYES
- 申请号:PCT/US2018/066579 申请日:2018-12-19
- 公开(公告)号:WO2019133399A1 公开(公告)日:2019-07-04
- 发明人: LIANG, Yongchao , MOUREAU, David , WALL, Brian , ZHAO, Lucy , HOLLINGER, Jonathan , BARTHOLOMEW, Glenn P.
- 申请人: BECTON, DICKINSON AND COMPANY
- 申请人地址: 1 Becton Drive MC110 Franklin Lakes, New Jersey 07417-1880 US
- 专利权人: BECTON, DICKINSON AND COMPANY
- 当前专利权人: BECTON, DICKINSON AND COMPANY
- 当前专利权人地址: 1 Becton Drive MC110 Franklin Lakes, New Jersey 07417-1880 US
- 代理机构: FIELD, Bret E.
- 优先权: US62/610,478 20171226
- 主分类号: C09B69/10
- IPC分类号: C09B69/10
摘要:
Water solvated polymeric dyes having a deep ultraviolet excitation spectrum are provided. The subject polymeric dyes include a light harvesting multichromophore having conjugation-modifying repeat units incorporated into the polymer backbone to provide segments of π-conjugated co-monomers having limited π-conjugation between segments. Polymeric tandem dyes are also provided that further include a signaling chromophore covalently linked to the multichromophore in energy-receiving proximity therewith. Also provided are labelled specific binding members that include the subject water solvated polymeric dyes. Methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule in which the subject polymeric dyes find use are also provided. Systems and kits for practicing the subject methods are also provided.
IPC结构图谱:
C | 化学;冶金 |
--C09 | 染料;涂料;抛光剂;天然树脂;黏合剂;其他类目不包含的组合物;其他类目不包含的材料的应用 |
----C09B | 有机染料或用于制造染料的有关化合物;媒染剂;色淀 |
------C09B69/00 | 不包含在本小类任一单独的组内的染料 |
--------C09B69/10 | .聚合的染料;染料与单体或高分子化合物的反应产物 |