发明申请
WO2019022487A1 INTERMEDIATES USEFUL FOR THE SYNTHESIS OF A SELECTIVE INHIBITOR AGAINST PROTEIN KINASE AND PROCESSES FOR PREPARING THE SAME
审中-公开
基本信息:
- 专利标题： INTERMEDIATES USEFUL FOR THE SYNTHESIS OF A SELECTIVE INHIBITOR AGAINST PROTEIN KINASE AND PROCESSES FOR PREPARING THE SAME
- 申请号：PCT/KR2018/008383 申请日：2018-07-25
- 公开(公告)号：WO2019022487A1 公开(公告)日：2019-01-31
- 发明人： OH, Sang-Ho , KHOO, Ja-Heouk , LIM, Jong-Chul , LEE, Doo-Byung , LEE, Jung-Ae , LEE, Jun-Sup , JU, Hyun , SHIN, Woo-Seob , JEON, Sang-Seol
- 申请人： YUHAN CORPORATION
- 申请人地址： 74, Noryangjin-ro Dongjak-gu Seoul 06927 KR
- 专利权人： YUHAN CORPORATION
- 当前专利权人： YUHAN CORPORATION
- 当前专利权人地址： 74, Noryangjin-ro Dongjak-gu Seoul 06927 KR
- 代理机构： OH, Kook-Jin
- 优先权： KR10-2017-0096226 20170728
- 主分类号： C07D403/04
- IPC分类号： C07D403/04 ; A61K31/506 ; C07D413/14
摘要：
The present invention provides intermediates useful for the synthesis of an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors; and processes for preparing the same. And also, the present invention provides novel intermediates useful for said process and processes for preparing the same.
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D403/00 | 杂环化合物，含有两个或更多的杂环，以氮原子作为仅有的杂环原子，C07D401/00组不包含的 |
| --------C07D403/02 | .含两个杂环 |
| ----------C07D403/04 | ..被环原子—环原子的键直接连接的 |