基本信息:
- 专利标题： SOLID FORMS OF OBETICHOLIC ACID AND PROCESS FOR PREPARATION
- 申请号：PCT/IB2018/053377 申请日：2018-05-15
- 公开(公告)号：WO2018211413A1 公开(公告)日：2018-11-22
- 发明人： PATHIVADA, Deepika , MUDAPAKA, Vamsi Krishna , GUPTA, Anish
- 申请人： DR. REDDY’S LABORATORIES LIMITED
- 申请人地址： 8-2-337, Road No. 3, Banjara Hills Hyderabad, Telangana 500034 IN
- 专利权人： DR. REDDY’S LABORATORIES LIMITED
- 当前专利权人： DR. REDDY’S LABORATORIES LIMITED
- 当前专利权人地址： 8-2-337, Road No. 3, Banjara Hills Hyderabad, Telangana 500034 IN
- 优先权： IN201741016891 20170515
- 主分类号： A61K31/575
- IPC分类号： A61K31/575 ; C07J9/00 ; A61P1/16
摘要：
The invention of the present application relates to crystalline forms of obeticholic acid and process for preparation thereof. Specifically, the invention of present application relates to crystalline forms VD1, VD2, VD3, VD4 and VD5 of obeticholic acid. Specifically, crystalline form VD2 is stable and has excellent physic-chemical properties. Crystalline form VD2 is may be easily formulated into a pharmaceutical composition comprising obeticholic acid.
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K31/00 | 含有机有效成分的医药配制品 |
| --------A61K31/33 | .杂环化合物 |
| ----------A61K31/575 | ..17β位由含3个或3个以上碳原子的链取代的，例如胆烷、胆甾烷、麦角甾醇、谷甾醇 |