发明申请
WO2018195473A1 COMBINATIONS INCLUDING BETA-ADRENORECEPTOR AGONISTS FOR TREATMENT OF PARKINSON'S DISEASE AND MOVEMENT DISORDERS
审中-公开
基本信息:
- 专利标题： COMBINATIONS INCLUDING BETA-ADRENORECEPTOR AGONISTS FOR TREATMENT OF PARKINSON'S DISEASE AND MOVEMENT DISORDERS
- 申请号：PCT/US2018/028639 申请日：2018-04-20
- 公开(公告)号：WO2018195473A1 公开(公告)日：2018-10-25
- 发明人： SCHERZER, Clemens
- 申请人： THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
- 申请人地址： 75 Francis Street Boston, Massachusetts 02115 US
- 专利权人： THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
- 当前专利权人： THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
- 当前专利权人地址： 75 Francis Street Boston, Massachusetts 02115 US
- 代理机构： DEYOUNG, Janice Kugler et al.
- 优先权： US62/487,541 20170420
- 主分类号： A61P25/16
- IPC分类号： A61P25/16 ; A61P25/14 ; C07D473/12
摘要：
Provided herein are methods of treating a subject who has a synucleinopathy (e.g., Parkinson's disease) that include: administering to a subject in need of such treatment therapeutically effective amounts of a β2-adrenoreceptor agonist and at least one therapeutic agent selected from the group consisting of: a synucleinopathy therapeutic agent, a β2-adrenoreceptor antagonist and a health supplement, wherein the health supplement is selected from the group consisting of caffeine, inosine, creatine, coenzyme Q10, vitamin E, and omega-3 fatty acids, to thereby treat Parkinson's disease in the subject.
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61P | 化合物或药物制剂的治疗活性 |
| ------A61P25/00 | 治疗神经系统疾病的药物 |
| --------A61P25/08 | .抗癫痫药；抗惊厥药 |
| ----------A61P25/16 | ..抗帕金森病的药物 |