基本信息:
- 专利标题： NANOPROBE-METAL CHELATOR COMPLEXES
- 申请号：PCT/US2017/039888 申请日：2017-06-29
- 公开(公告)号：WO2018147894A1 公开(公告)日：2018-08-16
- 发明人： CHOI, Hak Soo , KIM, Jonghan , EL FAKHRI, Georges
- 申请人： THE GENERAL HOSPITAL CORPORATION , NORTHEASTERN UNIVERSITY , CHOI, Hak Soo , KIM, Jonghan , EL FAKHRI, Georges
- 申请人地址： 55 Fruit Street Boston, Massachusetts 02114 US
- 专利权人： THE GENERAL HOSPITAL CORPORATION,NORTHEASTERN UNIVERSITY,CHOI, Hak Soo,KIM, Jonghan,EL FAKHRI, Georges
- 当前专利权人： THE GENERAL HOSPITAL CORPORATION,NORTHEASTERN UNIVERSITY,CHOI, Hak Soo,KIM, Jonghan,EL FAKHRI, Georges
- 当前专利权人地址： 55 Fruit Street Boston, Massachusetts 02114 US
- 代理机构： DAVEY, Evan A. et al.
- 优先权： US62/456,210 20170208
- 主分类号： C09B23/04
- IPC分类号： C09B23/04 ; A61L17/12 ; C09B23/10
摘要：
Provided herein are compounds that are able to bind metal ions ( e.g. , free metal ions or metal ions bound to low affinity ligands) in a sample or subject. Also provided herein are methods of using the compounds for chelating metal ions and for the treatment of diseases associated with abnormal levels of metal ions. Methods of preparing the compounds and pharmaceutical compositions are also provided.
IPC结构图谱:
| C | 化学；冶金 |
| --C09 | 染料；涂料；抛光剂；天然树脂；黏合剂；其他类目不包含的组合物；其他类目不包含的材料的应用 |
| ----C09B | 有机染料或用于制造染料的有关化合物；媒染剂；色淀 |
| ------C09B23/00 | 甲川基或多甲川基染料，例如菁染料 |
| --------C09B23/01 | .以甲川基链为特征的 |
| ----------C09B23/02 | ..含有奇数的CH基 |
| ------------C09B23/04 | ...1个CH基，如菁、异菁、假菁 |