基本信息:
- 专利标题： COMPOUNDS
- 申请号：PCT/CN2018/073846 申请日：2018-01-23
- 公开(公告)号：WO2018137619A1 公开(公告)日：2018-08-02
- 发明人： REN, Feng , SANG, Yingxia , XING, Weiqiang , ZHAN, Yang , ZHAO, Baowei
- 申请人： GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED , GLAXOSMITHKLINE (CHINA) R&D COMPANY LIMITED
- 申请人地址： 980 Great West Road Brentford, Middlesex TW8 9GS GB
- 专利权人： GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED,GLAXOSMITHKLINE (CHINA) R&D COMPANY LIMITED
- 当前专利权人： GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED,GLAXOSMITHKLINE (CHINA) R&D COMPANY LIMITED
- 当前专利权人地址： 980 Great West Road Brentford, Middlesex TW8 9GS GB
- 代理机构： KING & WOOD MALLESONS
- 优先权： CNPCT/CN2017/072587 20170125; CNPCT/CN2017/072610 20170125; CNPCT/CN2017/072612 20170125
- 主分类号： C07D413/14
- IPC分类号： C07D413/14 ; A61K31/5377 ; A61P25/16 ; A61P25/28
摘要：
The present invention provides novel compounds that inhibit LRRK2 kinase activity, processes for their preparation, compositions containing them and their use in the treatment of or prevention of diseases associated with or characterized by LRRK2 kinase activity, for example Parkinson's disease, Alzheimer's disease and amyotrophic lateral sclerosis (ALS).
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D413/00 | 杂环化合物，含两个或更多个杂环，至少有1个环有氮原子和氧原子作为仅有的杂环原子 |
| --------C07D413/14 | .含有3个或更多个杂环 |