基本信息:
- 专利标题: PRODUCTION OF PROTEINS IN LABYRINTHULOMYCETES
- 专利标题(中):迷迭香属植物中蛋白质的生产
- 申请号:PCT/US2017/022539 申请日:2017-03-15
- 公开(公告)号:WO2017161005A1 公开(公告)日:2017-09-21
- 发明人: CAIAZZA, Nicky C. , URANO, Jun , WIN, Maung N. , BOLES, Kent S.
- 申请人: SYNTHETIC GENOMICS, INC.
- 申请人地址: Synthetic Genomics, Inc. 11149 North Torrey Pines Road, Suite 100 La Jolla, CA 92037 US
- 专利权人: SYNTHETIC GENOMICS, INC.
- 当前专利权人: SYNTHETIC GENOMICS, INC.
- 当前专利权人地址: Synthetic Genomics, Inc. 11149 North Torrey Pines Road, Suite 100 La Jolla, CA 92037 US
- 代理机构: HAILE, Lisa A. et al.
- 优先权: US62/309,402 20160316
- 主分类号: C07K14/705
- IPC分类号: C07K14/705 ; C12N15/79
摘要:
The present invention provides recombinant host cells that produce proteins or therapeutic proteins, and nucleic acid constructs for producing the cells. The cells have nucleic acid constructs that encode a heterologous protein, for example an antibody. The nucleic acid constructs also can have a functional signal sequence that directs the secretion of the protein from the cell. The signal sequence can be any functional signal sequence, and various signal sequences are disclosed herein. The invention also provides methods of producing the proteins.
摘要(中):
本发明提供了产生蛋白质或治疗性蛋白质的重组宿主细胞,以及用于产生该细胞的核酸构建体。 细胞具有编码异源蛋白质的核酸构建体,例如抗体。 核酸构建体也可具有指导蛋白质从细胞分泌的功能性信号序列。 信号序列可以是任何功能性信号序列,并且本文公开了各种信号序列。 本发明还提供了生产蛋白质的方法。 p>
IPC结构图谱:
C | 化学;冶金 |
--C07 | 有机化学 |
----C07K | 肽 |
------C07K14/00 | 具有多于20个氨基酸的肽;促胃液素;生长激素释放抑制因子;促黑激素;其衍生物 |
--------C07K14/415 | .来自植物 |
----------C07K14/705 | ..受体、细胞表面抗原;细胞表面决定因子 |