发明申请
WO2017040695A1 METHOD OF IDENTIFYING THE PRESENCE OF FOREIGN ALLELES IN A DESIRED HAPLOTYPE
审中-公开
基本信息:
- 专利标题: METHOD OF IDENTIFYING THE PRESENCE OF FOREIGN ALLELES IN A DESIRED HAPLOTYPE
- 专利标题(中):识别出所需要的外来人物的存在方法
- 申请号:PCT/US2016/049746 申请日:2016-08-31
- 公开(公告)号:WO2017040695A1 公开(公告)日:2017-03-09
- 发明人: SONSTEGARD, Tad, S. , FAHRENKRUG, Scott, C. , CARLSON, Daniel, F.
- 申请人: RECOMBINETICS, INC.
- 申请人地址: 1246 University Avenue West Suite 301 Saint Paul, MN 55104 US
- 专利权人: RECOMBINETICS, INC.
- 当前专利权人: RECOMBINETICS, INC.
- 当前专利权人地址: 1246 University Avenue West Suite 301 Saint Paul, MN 55104 US
- 代理机构: HERBERT, Curtis, B. et al.
- 优先权: US62/212,840 20150901; US62/321,942 20160413
- 主分类号: A01K67/027
- IPC分类号: A01K67/027 ; C12N15/87
摘要:
Methods and kits to determine the presence of exogenous alleles within a native haplotype are provided. Introduction of foreign alleles into livestock genomes has provided the ability to introduce specific desirable traits. The present disclosure provides methods to identify the presence of exogenous alleles that foreign to a haplotype at a target locus, and identify specific markers that are native to the haplotype. Identification of exogenous genes at a target locus, flanked by native markers is indicative that the exogenous gene is present through molecular engineering. Conversely, the presence of an exogenous gene that are only partially flanked by native markers is indicative that the allele is present due to sexual breeding.
摘要(中):
提供了确定天然单体型外源性等位基因存在的方法和试剂盒。 将外来等位基因引入家畜基因组提供了引入特定的所需性状的能力。 本公开提供了鉴定在目标基因座处单倍型外源的外源等位基因的存在的方法,并鉴定了该单体型天然的特异性标记。 通过天然标记鉴定位于靶基因座的外源基因,表明通过分子工程存在外源基因。 相反地,只有部分被天然标记侧翼的外源基因的存在表明由于性繁殖而存在等位基因。
IPC结构图谱:
A | 人类生活必需 |
--A01 | 农业;林业;畜牧业;狩猎;诱捕;捕鱼 |
----A01K | 畜牧业;禽类、鱼类、昆虫的管理;捕鱼;饲养或养殖其他类不包含的动物;动物的新品种 |
------A01K67/00 | 饲养或养殖其他类不包含的动物;动物新品种 |
--------A01K67/027 | .脊椎动物的新品种 |