基本信息:
- 专利标题: PROCESS FOR PRINTING 3D TISSUE CULTURE MODELS
- 专利标题(中):打印3D组织文化模型的过程
- 申请号:PCT/AU2016/000258 申请日:2016-07-21
- 公开(公告)号:WO2017011854A1 公开(公告)日:2017-01-26
- 发明人: O'MAHONY, Aidan Patrick , UTAMA, Robert Hadinoto , FIFE, Christopher Michael , ATAPATTU, Lakmali , RIBEIRO, Julio Cesar Caldeira
- 申请人: INVENTIA LIFE SCIENCE PTY LTD
- 申请人地址: PO Box 653 Surry Hills NSW 2010 AU
- 专利权人: INVENTIA LIFE SCIENCE PTY LTD
- 当前专利权人: INVENTIA LIFE SCIENCE PTY LTD
- 当前专利权人地址: PO Box 653 Surry Hills NSW 2010 AU
- 代理机构: ALLENS PATENT & TRADE MARK ATTORNEYS
- 优先权: AU2015902917 20150722
- 主分类号: C12N5/02
- IPC分类号: C12N5/02 ; A61L27/52
摘要:
A process for producing a 3D tissue culture model by (a) printing a drop of bio-ink to a substrate; (b) printing a drop of activator to the drop of bio-ink to form a hydrogel droplet; (c) repeating steps (a) and (b) in any order to form a hydrogel mold adapted to receive a drop containing cells; (d) printing a drop containing cells to the hydrogel mold; and (e) repeating steps (a) and (b) in any order to form a 3D tissue culture model comprising the cells encapsulated in the hydrogel mold.
摘要(中):
一种通过(a)将一滴生物油墨印刷到基底上来生产3D组织培养模型的方法; (b)将一滴活化剂印刷到生物油墨滴上以形成水凝胶液滴; (c)以任何顺序重复步骤(a)和(b)以形成适于接收含有细胞的液滴的水凝胶模具; (d)将含有细胞的液滴印刷到水凝胶模具上; 和(e)以任何顺序重复步骤(a)和(b)以形成包含封装在水凝胶模具中的细胞的3D组织培养模型。