基本信息:
- 专利标题: VECTORS
- 专利标题(中):向量
- 申请号:PCT/SG2016/050258 申请日:2016-06-02
- 公开(公告)号:WO2016195598A1 公开(公告)日:2016-12-08
- 发明人: PATZEL, Volker
- 申请人: NATIONAL UNIVERSITY OF SINGAPORE
- 申请人地址: 21 Lower Kent Ridge Road Singapore 119077 SG
- 专利权人: NATIONAL UNIVERSITY OF SINGAPORE
- 当前专利权人: NATIONAL UNIVERSITY OF SINGAPORE
- 当前专利权人地址: 21 Lower Kent Ridge Road Singapore 119077 SG
- 代理机构: AMICA LAW LLC
- 优先权: GB1509578.9 20150603
- 主分类号: C12N15/85
- IPC分类号: C12N15/85 ; C12N15/64
摘要:
We disclose dumbbell-shaped vectors adapted for efficient expression in mammalian cells. We also disclose a novel method allowing the efficient synthesis of dumbbell-shaped vectors at low cost for delivery of recombinant DNA and RNA into host cells; and the use of dumbbell-shaped vectors for transient expression in, for example, primary human cells.
摘要(中):
我们公开了适合在哺乳动物细胞中有效表达的哑铃形载体。 我们还公开了一种允许低成本有效合成哑铃形载体的新方法,用于将重组DNA和RNA递送到宿主细胞中; 以及使用哑铃形载体用于例如原代人细胞中的瞬时表达。