基本信息:
- 专利标题： LEPIDOPTERAN-ACTIVE CRY1DA1 AMINO ACID SEQUENCE VARIANT PROTEINS
- 专利标题（中）：LEPIDOPTERAN活性CRY1DA1氨基酸序列变异蛋白
- 申请号：PCT/US2015055779 申请日：2015-10-15
- 公开(公告)号：WO2016061377A3 公开(公告)日：2016-08-04
- 发明人： BAUM JAMES A , CERRUTI THOMAS , FLASINSKI STANISLAW , FU XIAORAN , HOWE ARLENE R , SALVADOR SARA ANN
- 申请人： MONSANTO TECHNOLOGY LLC
- 专利权人： MONSANTO TECHNOLOGY LLC
- 当前专利权人： MONSANTO TECHNOLOGY LLC
- 优先权： US201462064994 2014-10-16; US201462065017 2014-10-17
- 主分类号： C12N15/82
- IPC分类号： C12N15/82 ; A01H5/00 ; C07K14/325
摘要：
Engineered Cry1Da amino acid sequences are provided that exhibit improved Lepidopteran insecticidal activity and an enhanced Lepidopteran spectrum compared to the naturally occurring Cry1Da protein toxin. Polynucleotide sequences intended for use in expression of the improved proteins in plants are also provided. Particular embodiments provide compositions containing insect inhibitory amounts of the engineered proteins, as well as recombinant plants, plant parts, and seeds containing polynucleotide constructs encoding one or more of the improved engineered proteins.
摘要（中）：
提供了与天然存在的Cry1Da蛋白毒素相比表现出改进的鳞翅目杀虫活性和增强的鳞翅目光谱的工程化Cry1Da氨基酸序列。 还提供了用于在植物中表达改良蛋白质的多核苷酸序列。 具体实施方案提供了含有昆虫抑制量的工程改造蛋白质的组合物，以及含有编码一种或多种改进的工程化蛋白质的多核苷酸构建体的重组植物，植物部分和种子。