发明申请
WO2015130221A1 METHODS FOR REDUCING AGGREGATE CONTENT OF PROTEIN PREPARATIONS BY TREATMENT WITH ARYL ANIONS
审中-公开
基本信息:
- 专利标题： METHODS FOR REDUCING AGGREGATE CONTENT OF PROTEIN PREPARATIONS BY TREATMENT WITH ARYL ANIONS
- 专利标题（中）：通过用ARYL ANIONS处理来降低蛋白质制剂聚集含量的方法
- 申请号：PCT/SG2014/000085 申请日：2014-02-27
- 公开(公告)号：WO2015130221A1 公开(公告)日：2015-09-03
- 发明人： GAGNON, Peter Stanley
- 申请人： AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
- 申请人地址： 20 Biopolis Way, Centros 06-01 Singapore 138668 SG
- 专利权人： AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
- 当前专利权人： AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
- 当前专利权人地址： 20 Biopolis Way, Centros 06-01 Singapore 138668 SG
- 代理机构： SPRUSON & FERGUSON (ASIA) PTE LTD
- 主分类号： C07K1/18
- IPC分类号： C07K1/18 ; B01D15/36
摘要：
A method of reducing the aggregate content in a preparation having a target protein includes contacting the preparation with an aryl anion to form a mixture and contacting the mixture with at least one electropositive solid to remove excess aryl anion.
摘要（中）：
降低具有靶蛋白的制剂中聚集体含量的方法包括使制剂与芳基阴离子接触以形成混合物，并使该混合物与至少一种正电性固体接触以除去过量的芳基阴离子。