发明申请
WO2015003662A9 TRADITIONAL CHINESE MEDICINE COMPOSITION, AND PREPARATION AND APPLICATION THEREOF
审中-公开
基本信息:
- 专利标题: TRADITIONAL CHINESE MEDICINE COMPOSITION, AND PREPARATION AND APPLICATION THEREOF
- 专利标题(中):传统中医药组合物及其制备及应用
- 申请号:PCT/CN2014082105 申请日:2014-07-11
- 公开(公告)号:WO2015003662A9 公开(公告)日:2015-04-23
- 发明人: YAN XIJUN , WU NAIFENG , YAN KAIJING , YE ZHENGLIANG , ZHANG SHUNNAN , ZHOU LIHONG , ZHANG WENSHENG , DONG HAI OU , ZHENG YONGFENG , FAN LIJUN
- 申请人: TASLY PHARMACEUTICAL GROUP CO
- 专利权人: TASLY PHARMACEUTICAL GROUP CO
- 当前专利权人: TASLY PHARMACEUTICAL GROUP CO
- 优先权: CN201310290968 2013-07-11; CN201310384234 2013-08-29; CN201410044675 2014-01-30; CN201410085690 2014-03-10
- 主分类号: A61K36/537
- IPC分类号: A61K36/537 ; A61K9/20 ; A61K31/045 ; A61K31/343 ; A61K31/58 ; A61K31/7048 ; A61K36/258 ; A61P9/10
摘要:
A traditional Chinese medicine composition and a preparation thereof, and in particular, a micro drop pill. The traditional Chinese medicine composition comprises 50.0% to 99.9% of salvia miltiorrhiza and Panax notoginseng extract and 0.1% to 50.0% of borneol (by weight percentage). The salvia miltiorrhiza and Panax notoginseng extract comprises the following components (by weight percentage): salvianic acid A: salvianolic acid T: protocatechuic aldehyde: salvianolic acid D: rosmarinic acid: salvianolic acid B: salvianolic acid A: Notoginsenoside R1: ginsenoside Rg1: ginsenoside Re: ginsenoside Rb1: ginsenoside Rd: dihydrotanshinoneI: tanshinone I: cryptotanshinone: tanshinone IIΑ = (2-5): (0.5-1.9): (1.1-3): (0.2-1.2): (0.2-1): (0.5-2): (0.5-2): (0.2-1): (1.5-4): (0.1-0.5): (1-3.9): (0.1-1): (0.01-0.05): (0.05-0.1): (0.02-0.1): (0.1-0.5). A preparation method for the micro drop pill comprises vibration dropping, air cooling, and the like. The method can be used to manufacture drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity. The composition has an effect of treating acute myocardial ischemia and acute myocardial infarction.
摘要(中):
一种中药组合物及其制剂,特别是微滴丸。 中药组合物含有丹参和三七提取物50.0%〜99.9%,冰片0.1%〜50.0%(按重量百分比计)。 丹参和三七提取物含有以下组分(重量百分数):salvianic acid A:salvianolic acid T:原儿茶醛:salvianolic acid D:迷迭香酸:salvianolic acid B:salvianolic acid A:三七皂苷R1:人参皂甙Rg1:人参皂甙 Re:人参皂苷Rb1:人参皂苷Rd:二氢丹参酮I:丹参酮I:隐丹参酮:丹参酮IIA =(2-5):(0.5-1.9):(1.1-3):(0.2-1.2):(0.2-1) -2):(0.5-2):(0.2-1):(1.5-4):(0.1-0.5):(1-3.9):(0.1-1):(0.01-0.05):(0.05-0.1 ):(0.02-0.1):(0.1-0.5)。 微滴丸的制备方法包括振动降落,空气冷却等。 该方法可用于制造具有高药物负载能力的滴丸,包衣药丸和滴丸胶囊。 该组合物具有治疗急性心肌缺血和急性心肌梗死的作用。
IPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K36/00 | 含有来自藻类、苔藓、真菌或植物或其派生物,例如传统草药的未确定结构的药物制剂 |
--------A61K36/18 | .被子植物亚门 |
----------A61K36/185 | ..双子叶植物纲 |
------------A61K36/53 | ...唇形科,如百里香,迷迭香或熏衣草 |
--------------A61K36/537 | ....鼠尾草属(鼠尾草) |