发明申请
WO2014150633A1 IMMOBILIZED KETOREDUCTASES AND PROCESS FOR MAKING AND USING IMMOBILIZED KETOREDUCTASE
审中-公开
基本信息:
- 专利标题： IMMOBILIZED KETOREDUCTASES AND PROCESS FOR MAKING AND USING IMMOBILIZED KETOREDUCTASE
- 专利标题（中）：固定化的糖浆和制造和使用固定化的热解糖的方法
- 申请号：PCT/US2014/023844 申请日：2014-03-12
- 公开(公告)号：WO2014150633A1 公开(公告)日：2014-09-25
- 发明人： TRUPPO, Matthew, D. , LI, Hongmei , MONCECCHI, Johannah, R. , STROTMAN, Hallena
- 申请人： MERCK SHARP & DOHME CORP. , TRUPPO, Matthew, D. , LI, Hongmei , MONCECCHI, Johannah, R. , STROTMAN, Hallena
- 申请人地址： 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 US
- 专利权人： MERCK SHARP & DOHME CORP.,TRUPPO, Matthew, D.,LI, Hongmei,MONCECCHI, Johannah, R.,STROTMAN, Hallena
- 当前专利权人： MERCK SHARP & DOHME CORP.,TRUPPO, Matthew, D.,LI, Hongmei,MONCECCHI, Johannah, R.,STROTMAN, Hallena
- 当前专利权人地址： 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 US
- 代理机构： MERCK SHARP & DOHME CORP.
- 优先权： US61/791,247 20130315; US61/898,503 20131101
- 主分类号： C12N9/04
- IPC分类号： C12N9/04
摘要：
The invention is directed to immobilized ketoreductases and methods of making and using them. Enzymes are protein molecules which serve to accelerate the chemical reactions of living cells (often by several orders of magnitude). Without enzymes, most biochemical reactions would be too slow to even carry out life processes. Enzymes display great specificity and are not permanently modified by their participation in reactions. Since they are not changed during the reactions, enzymes can be cost effectively used as catalysts for a desired chemical transformation.
摘要（中）：
本发明涉及固定的酮还原酶及其制备和使用方法。 酶是蛋白质分子，用于加速活细胞的化学反应（通常是几个数量级）。 没有酶，大多数生物化学反应将太慢，甚至不能进行生命过程。 酶显示出极大的特异性，并且不被参与反应永久地改变。 由于它们在反应期间没有改变，因此可以成本有效地使用酶作为所需化学转化的催化剂。