发明申请
WO2014100857A8 VACCINES FOR THE TREATMENT OF CANCER AND COMPOSITIONS FOR ENHANCING VACCINE EFFICACY
审中-公开
基本信息:
- 专利标题： VACCINES FOR THE TREATMENT OF CANCER AND COMPOSITIONS FOR ENHANCING VACCINE EFFICACY
- 专利标题（中）：用于治疗癌症和组合物以提高疫苗效能的疫苗
- 申请号：PCT/AU2013001523 申请日：2013-12-24
- 公开(公告)号：WO2014100857A8 公开(公告)日：2014-11-06
- 发明人： DAVEY ROSS ARTHUR , WEIR CHRISTOPHER JOHN , VESEY GRAHAM
- 申请人： CELL IDEAS PTY LTD , NORTHERN SYDNEY LOCAL HEALTH DISTR
- 专利权人： CELL IDEAS PTY LTD,NORTHERN SYDNEY LOCAL HEALTH DISTR
- 当前专利权人： CELL IDEAS PTY LTD,NORTHERN SYDNEY LOCAL HEALTH DISTR
- 优先权： AU2012905667 2012-12-24; AU2012905669 2012-12-24; AU2013903592 2013-09-18
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K38/00 ; A61P35/00 ; C12N5/077 ; C12N5/0775
摘要：
The present invention relates to the treatment and prevention of cancer. The present invention relates to vaccines comprising solubilized components of cancer cells or cancer- associated cells. Moreover, the present invention also relates to methods of producing vaccines from biological samples comprising cancer cells or cancer-associated cells and using said vaccines for the treatment or prevention of cancer in subjects. The present invention also relates to methods of producing vaccines, in particular, autologous vaccines. The present invention also relates to therapeutic uses of mesenchymal stem cells and to methods of treatment and or prevention that comprise administering mesenchymal stem cells to a subject. The present invention also relates to methods of enhancing the efficacy of vaccines and methods for the treatment and prevention of cancer, and to compositions and kits suitable for use in the methods.
摘要（中）：
本发明涉及癌症的治疗和预防。 本发明涉及包含癌细胞或癌相关细胞的溶解组分的疫苗。 此外，本发明还涉及从包含癌细胞或癌相关细胞的生物样品生产疫苗的方法，并且使用所述疫苗来治疗或预防受试者中的癌症。 本发明还涉及生产疫苗，特别是自体疫苗的方法。 本发明还涉及间充质干细胞的治疗用途以及包括向受试者施用间充质干细胞的治疗和/或预防方法。 本发明还涉及增强用于治疗和预防癌症的疫苗和方法的效力的方法以及适用于该方法的组合物和试剂盒。
公开/授权文献:
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K39/00 | 含有抗原或抗体的医药配制品 |