基本信息:
- 专利标题： NOVEL COMPOUNDS THAT ARE ERK INHIBITORS
- 专利标题（中）：新的化合物是ERK抑制剂
- 申请号：PCT/US2012/061836 申请日：2012-10-25
- 公开(公告)号：WO2013063214A1 公开(公告)日：2013-05-02
- 发明人： LIM, Jongwon , KELLEY, Elizabeth Helen , METHOT, Joey, L. , ZHOU, Hua , PETROCCHI, Alessia , MANSOOR, Umar Faruk , FISCHER, Christian , O'BOYLE, Brendan, M. , GUERIN, David Joseph , BIENSTOCK, Corey, E. , BOYCE, Christopher, W. , DANIELS, Matthew, H. , FALCONE, Danielle , FERGUSON, Ronald, D., II , FEVRIER, Salem , HUANG, Xianhai , LIPFORD, Kathryn Ann , SLOMAN, David, L. , WILSON, Kevin , ZHOU, Wei , WITTER, David , MALETIC, Milana, M. , SILIPHAIVANH, Phieng
- 申请人： MERCK SHARP & DOHME CORP. , LIM, Jongwon , KELLEY, Elizabeth Helen , METHOT, Joey, L. , ZHOU, Hua , PETROCCHI, Alessia , MANSOOR, Umar Faruk , FISCHER, Christian , O'BOYLE, Brendan, M. , GUERIN, David Joseph , BIENSTOCK, Corey, E. , BOYCE, Christopher, W. , DANIELS, Matthew, H. , FALCONE, Danielle , FERGUSON, Ronald, D., II , FEVRIER, Salem , HUANG, Xianhai , LIPFORD, Kathryn Ann , SLOMAN, David, L. , WILSON, Kevin , ZHOU, Wei , WITTER, David , MALETIC, Milana, M. , SILIPHAIVANH, Phieng
- 申请人地址： 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 US
- 专利权人： MERCK SHARP & DOHME CORP.,LIM, Jongwon,KELLEY, Elizabeth Helen,METHOT, Joey, L.,ZHOU, Hua,PETROCCHI, Alessia,MANSOOR, Umar Faruk,FISCHER, Christian,O'BOYLE, Brendan, M.,GUERIN, David Joseph,BIENSTOCK, Corey, E.,BOYCE, Christopher, W.,DANIELS, Matthew, H.,FALCONE, Danielle,FERGUSON, Ronald, D., II,FEVRIER, Salem,HUANG, Xianhai,LIPFORD, Kathryn Ann,SLOMAN, David, L.,WILSON, Kevin,ZHOU, Wei,WITTER, David,MALETIC, Milana, M.,SILIPHAIVANH, Phieng
- 当前专利权人： MERCK SHARP & DOHME CORP.,LIM, Jongwon,KELLEY, Elizabeth Helen,METHOT, Joey, L.,ZHOU, Hua,PETROCCHI, Alessia,MANSOOR, Umar Faruk,FISCHER, Christian,O'BOYLE, Brendan, M.,GUERIN, David Joseph,BIENSTOCK, Corey, E.,BOYCE, Christopher, W.,DANIELS, Matthew, H.,FALCONE, Danielle,FERGUSON, Ronald, D., II,FEVRIER, Salem,HUANG, Xianhai,LIPFORD, Kathryn Ann,SLOMAN, David, L.,WILSON, Kevin,ZHOU, Wei,WITTER, David,MALETIC, Milana, M.,SILIPHAIVANH, Phieng
- 当前专利权人地址： 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 US
- 代理机构： MERCK SHARP & DOHME CORP.
- 优先权： US61/552,194 20111027
- 主分类号： A61K9/66
- IPC分类号： A61K9/66
摘要：
Disclosed are the ERK inhibitors of formula (1): and the pharmaceutically acceptable salts thereof. Also disclosed are methods of treating cancer using the compounds of formula (1).
摘要（中）：
公开了式（1）的ERK抑制剂及其药学上可接受的盐。 还公开了使用式（1）的化合物治疗癌症的方法。
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K9/00 | 以特殊物理形状为特征的医药配制品 |
| --------A61K9/10 | .分散液；乳剂 |
| ----------A61K9/50 | ..微型胶囊 |
| ------------A61K9/66 | ...含乳剂、分散液或溶液的 |