基本信息:
- 专利标题： CELL FATE CONVERSION OF DIFFERENTIATED SOMATIC CELLS INTO GLIAL CELLS
- 专利标题（中）：分化的体细胞转化为胶质细胞的细胞命运转化
- 申请号：PCT/US2011057762 申请日：2011-10-25
- 公开(公告)号：WO2012058243A2 公开(公告)日：2012-05-03
- 发明人： TESAR PAUL J , MILLER ROBERT H , NAJM FADI J
- 申请人： UNIV CASE WESTERN RESERVE , TESAR PAUL J , MILLER ROBERT H , NAJM FADI J
- 专利权人： UNIV CASE WESTERN RESERVE,TESAR PAUL J,MILLER ROBERT H,NAJM FADI J
- 当前专利权人： UNIV CASE WESTERN RESERVE,TESAR PAUL J,MILLER ROBERT H,NAJM FADI J
- 优先权： US40667010 2010-10-26
- 主分类号： C12N5/079
- IPC分类号： C12N5/079 ; C12N5/10 ; C12N15/85
摘要：
The present invention relates to the reprogramming of differentiated somatic cells, such as those differentiated cells that arise from embryonic mesoderm, into glial cells. Glial cells produced from this reprogramming are functionally equivalent to glial cells that arise from ectodermal origins.
摘要（中）：
本发明涉及分化的体细胞（例如由胚胎中胚层产生的分化细胞）重编程为神经胶质细胞。 由该重编程产生的神经胶质细胞在功能上等同于源自外胚层起源的神经胶质细胞。