基本信息:
- 专利标题： POLYCYCLIC COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS
- 申请号：PCT/US2010/050787 申请日：2010-09-29
- 公开(公告)号：WO2011041462A2 公开(公告)日：2011-04-07
- 发明人： CLARK, Ryan , STEARNS, Brian Andrew , SCOTT, Jill Melissa , COATE, Heather Renee , ZHAO, Lucy , SEIDERS, Thomas Jon , VOLKOTS, Deborah , ARRUDA, Jeannie M. , STOCK, Nicholas Simon , TRUONG, Yen Pham , ZALATAN, David Nathan
- 申请人： AMIRA PHARMACEUTICALS, INC. , CLARK, Ryan , STEARNS, Brian Andrew , SCOTT, Jill Melissa , COATE, Heather Renee , ZHAO, Lucy , SEIDERS, Thomas Jon , VOLKOTS, Deborah , ARRUDA, Jeannie M. , STOCK, Nicholas Simon , TRUONG, Yen Pham , ZALATAN, David Nathan
- 申请人地址： 9535 Waples Street Suite 100 San Diego, California 92121 US
- 专利权人： AMIRA PHARMACEUTICALS, INC.,CLARK, Ryan,STEARNS, Brian Andrew,SCOTT, Jill Melissa,COATE, Heather Renee,ZHAO, Lucy,SEIDERS, Thomas Jon,VOLKOTS, Deborah,ARRUDA, Jeannie M.,STOCK, Nicholas Simon,TRUONG, Yen Pham,ZALATAN, David Nathan
- 当前专利权人： AMIRA PHARMACEUTICALS, INC.,CLARK, Ryan,STEARNS, Brian Andrew,SCOTT, Jill Melissa,COATE, Heather Renee,ZHAO, Lucy,SEIDERS, Thomas Jon,VOLKOTS, Deborah,ARRUDA, Jeannie M.,STOCK, Nicholas Simon,TRUONG, Yen Pham,ZALATAN, David Nathan
- 当前专利权人地址： 9535 Waples Street Suite 100 San Diego, California 92121 US
- 代理机构： WILSON SONSINI GOODRICH & ROSATI et al.
- 优先权： US61/247,877 20091001
- 主分类号： C07D261/14
- IPC分类号： C07D261/14 ; C07D413/06 ; C07D413/04 ; C07D413/12 ; A61K31/42 ; A61K31/496 ; A61K31/4245 ; A61P11/06 ; A61P35/00
摘要：
Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D261/00 | 杂环化合物，含有1,2-唑环或氢化1,2-唑环 |
| --------C07D261/02 | .不与其他环稠合 |
| ----------C07D261/06 | ..环原子间或环原子与非环原子间有两个或更多个双键 |
| ------------C07D261/10 | ...有杂原子或有3个键连杂原子，其中最多有1个键连卤原子的碳原子，例如酯基或腈基，直接连在环碳原子上 |
| --------------C07D261/14 | ....氮原子 |