基本信息:
- 专利标题： GLASS CERAMIC SCAFFOLDS WITH COMPLEX TOPOGRAPHY
- 专利标题（中）：玻璃陶瓷SCAFFOLDS与复杂的地形
- 申请号：PCT/US2010/048209 申请日：2010-09-09
- 公开(公告)号：WO2011031821A1 公开(公告)日：2011-03-17
- 发明人： DENRY, Isabelle L.
- 申请人： THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION , DENRY, Isabelle L.
- 申请人地址： 1216 Kinnear Road Columbus, OH 43212 US
- 专利权人： THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION,DENRY, Isabelle L.
- 当前专利权人： THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION,DENRY, Isabelle L.
- 当前专利权人地址： 1216 Kinnear Road Columbus, OH 43212 US
- 代理机构： WIEDEMANN, John T.
- 优先权： US61/240,802 20090909
- 主分类号： A61F2/00
- IPC分类号： A61F2/00
摘要：
A bioactive and bioresorbable scaffold including a glass-ceramic material including fluoroapatite and hydroxyapatite doped with about 1-5 wt.% niobium oxide that is shaped into a scaffold is described. The glass-ceramic material has high crystallinity and a complex topography which provide it with greater structural strength and bioresorbability. Methods of preparing the bioactive and bioresorbable scaffold and methods of using the scaffold for musculoskeletal engineering are also provided.
摘要（中）：
描述了一种生物活性和生物可再吸收的支架，其包括包含氟磷灰石和掺杂有约1-5重量％的氧化铌的羟基磷灰石的玻璃 - 陶瓷材料，其被成形为支架。 玻璃陶瓷材料具有高结晶度和复杂的形貌，使其具有更大的结构强度和生物可再吸收性。 还提供了制备生物活性和生物可吸收支架的方法以及使用脚手架进行肌肉骨骼工程的方法。