基本信息:
- 专利标题： INHIBITORS OF PI3 KINASE AND / OR MTOR
- 专利标题（中）：PI3激酶和/或MTOR的抑制剂
- 申请号：PCT/US2010/032593 申请日：2010-04-27
- 公开(公告)号：WO2010126895A1 公开(公告)日：2010-11-04
- 发明人： ANDREWS, Kristin , BO, Yunxin, Y. , BOOKER, Shon , CEE, Victor, J. , D'ANGELO, Noel , HERBERICH, Bradley, J. , HONG, Fang-Tsao , JACKSON, Claire, L., M. , LANMAN, Brian, A. , LIAO, Hongyu , LIU, Longbin , NISHIMURA, Nobuko , NORMAN, Mark, H. , PETTUS, Liping, H. , REED, Anthony, B. , SMITH, Adrian, L. , TADESSE, Seifu , TAMAYO, Nuria, A. , WU, Bin , WURZ, Ryan , YANG, Kevin
- 申请人： AMGEN INC. , ANDREWS, Kristin , BO, Yunxin, Y. , BOOKER, Shon , CEE, Victor, J. , D'ANGELO, Noel , HERBERICH, Bradley, J. , HONG, Fang-Tsao , JACKSON, Claire, L., M. , LANMAN, Brian, A. , LIAO, Hongyu , LIU, Longbin , NISHIMURA, Nobuko , NORMAN, Mark, H. , PETTUS, Liping, H. , REED, Anthony, B. , SMITH, Adrian, L. , TADESSE, Seifu , TAMAYO, Nuria, A. , WU, Bin , WURZ, Ryan , YANG, Kevin
- 申请人地址： One Amgen Center Drive Thousand Oaks, CA 91320-1799 US
- 专利权人： AMGEN INC.,ANDREWS, Kristin,BO, Yunxin, Y.,BOOKER, Shon,CEE, Victor, J.,D'ANGELO, Noel,HERBERICH, Bradley, J.,HONG, Fang-Tsao,JACKSON, Claire, L., M.,LANMAN, Brian, A.,LIAO, Hongyu,LIU, Longbin,NISHIMURA, Nobuko,NORMAN, Mark, H.,PETTUS, Liping, H.,REED, Anthony, B.,SMITH, Adrian, L.,TADESSE, Seifu,TAMAYO, Nuria, A.,WU, Bin,WURZ, Ryan,YANG, Kevin
- 当前专利权人： AMGEN INC.,ANDREWS, Kristin,BO, Yunxin, Y.,BOOKER, Shon,CEE, Victor, J.,D'ANGELO, Noel,HERBERICH, Bradley, J.,HONG, Fang-Tsao,JACKSON, Claire, L., M.,LANMAN, Brian, A.,LIAO, Hongyu,LIU, Longbin,NISHIMURA, Nobuko,NORMAN, Mark, H.,PETTUS, Liping, H.,REED, Anthony, B.,SMITH, Adrian, L.,TADESSE, Seifu,TAMAYO, Nuria, A.,WU, Bin,WURZ, Ryan,YANG, Kevin
- 当前专利权人地址： One Amgen Center Drive Thousand Oaks, CA 91320-1799 US
- 代理机构： CRISSEY, Todd, M.
- 优先权： US61/173,520 20090428; US61/258,532 20091105
- 主分类号： C07D401/14
- IPC分类号： C07D401/14 ; C07D473/00 ; A61K31/52 ; A61P35/00
摘要：
The present invention relates to compounds of Formula I, or a pharmaceutically acceptable salt thereof; methods of treating diseases or conditions, such as cancer, using the compounds; and pharmaceutical compositions containing the compounds, wherein the variables are as defined herein.
摘要（中）：
本发明涉及式I化合物或其药学上可接受的盐; 使用该化合物治疗疾病或病症如癌症的方法; 和含有这些化合物的药物组合物，其中变量如本文所定义。
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D401/00 | 杂环化合物，含有两个或更多个杂环，以氮原子作为仅有的杂环原子，至少有1个环是仅含有1个氮原子的六元环 |
| --------C07D401/14 | .含有3个或更多个杂环 |